Lack of immunogenicity of hydrolysed wheat flour in patients with coeliac disease after a short ‐term oral challenge

ConclusionsWe confirm that fermentation of wheat flour with sourdough lactobacilli and fungal proteases is capable of abolishing the T cell immunogenicity of gluten in coeliac patients. Our data also validate the short‐term oral challenge as a useful tool for testing the efficacy of novel therapeutic approaches.

Source: Alimentary Pharmacology and Therapeutics - June 19, 2017 Category: Drugs & Pharmacology Authors: R. Mandile, S. Picascia, C. Parrella, A. Camarca, M. Gobbetti, L. Greco, R. Troncone, C. Gianfrani, R. Auricchio Tags: ORIGINAL ARTICLE Source Type: research