Sleep Apnea Killed Carrie Fisher. Could It Kill You Too?
The condition that killed Carrie Fisher may affect up to a quarter of middle-aged adults.
Conclusions: Medication alerts hold promise as a means of reducing opioid and benzodiazepine coprescribing among certain high-risk groups.
ConclusionsThe presence and the association of comorbidities seem to be higher in patients suffering from OSA, OS and OHS. Subjects suffering of OHS present a high prevalence of main diseases despite their younger age compared with others patients with SDB. Sleepiness may have a role, at least in a subset of these patients, into the development of comorbidities.
AbstractThe relationship between obstructive sleep apnea (OSA) and non-alcoholic fatty liver disease (NAFLD) has been an issue of great concern. The primary purpose of this study was to determine the influence of OSA on the levels of liver enzymes including alanine transaminase (ALT) and aspartate transaminase (AST). The secondary purpose was to estimate the effect of OSA on the histological lesions of NAFLD, such as steatosis, lobular inflammation, ballooning degeneration, fibrosis, as well as NAFLD activity score (NAS). A systematic literature review using PubMed, Cochrane Library, Embase, and Ovid technologies from Janu...
Conclusions: Prevalence of OSA was higher in this study compared to Indian studies hitherto. Since OSA is treatable, people with diabetes should be screened for this condition to reduce their CVD risk. PMID: 29322708 [PubMed - in process]
This study aimed to clarify the triggers of the non-dipper pattern in nocturnal BP in Japanese patients with severe OSA (the apnea-hypopnea index ≥30/h). Methods Of 541 patients with OSA diagnosed using polysomnography (PSG) and ambulatory BP monitoring (ABPM), 163 patients
Study Objectives:In children, the effect of the common phenotype of obstructive sleep apnea (OSA) on sleep architecture is not adequately documented. The aim of this study was to evaluate sleep architecture in a pediatric population with the common phenotype of OSA.Methods:The prospective cross-sectional study included 116 children in the age range of 3 to 8 years with suspected OSA and 51 healthy children. All children underwent standard overnight in-laboratory video polysomnography. Patients with obstructive apnea-hypopnea index≥ 1, adenotonsillar hypertrophy, a long face, narrow palate or minor malocclusions, and no ...
Conclusions:We failed to detect a difference in dream content between patients with sleep apnea and controls. Further studies are required to determine whether these results indicate that the incorporation of respiratory events into dreams is absent in patients with sleep apnea or represents a bias due to the collection of dream content in the early morning hours.Citation:Di Pauli F, Stefani A, Holzknecht E, Brandauer E, Mitterling T, Holzinger B, Högl B. Dream content in patients with sleep apnea: a prospective sleep laboratory study.J Clin Sleep Med. 2018;14(1):41–46.
Conclusions:Patients with mild to moderate OSA have significant neurobehavioral morbidity. During“gold standard” treatment, normal function was not achieved, even with adequate device usage. CPAP efficacy for improving sleepiness and neuropsychological function in this milder end of the OSA spectrum may be poor, which may affect CPAP adherence. These findings suggest that there may be neurological changes related to OSA that do not respond to CPAP treatment, the etiology of which requires further investigation.Citation:Jackson ML, McEvoy RD, Banks S, Barnes M. Neurobehavioral impairment and CPAP treatment respo...
Conclusions:Treatment-emergent or persistent CSA during CPAP reduced therapy adherence, but adherence improved early after switching from CPAP to ASV.Citation:Pépin JL, Woehrle H, Liu D, Shao S, Armitstead JP, Cistulli PA, Benjafield AV, Malhotra A. Adherence to positive airway therapy after switching from CPAP to ASV: a big data analysis.J Clin Sleep Med. 2018;14(1):57–63.
Conclusions:Prevalence of sleep apnea in our study was low, likely because of clinical underrecognition. Despite having more cardiovascular disease, the patients with acute stroke and sleep apnea had less severe neurological injury and lower unadjusted mortality than those without a history of sleep apnea.Citation:Festic N, Alejos D, Bansal V, Mooney L, Fredrickson PA, Castillo PR, Festic E. Sleep apnea in patients hospitalized with acute ischemic stroke: underrecognition and associated clinical outcomes.J Clin Sleep Med. 2018;14(1):75–80.