Carrie Fisher's Autopsy Findings Point Out Links Between Sleep Apnea And Drug Use, Heart Disease

Carrie Fisher's autopsy findings raise questions about the interplay of sleep apnea, drug use and heart disease.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news

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The road to poor health is often paved with good intentions. Most of us know what we should do in order to feel better and live healthier, but that doesn't mean we're going to do it. That makes it really hard for our doctors to do their job, especially if we're dealing with a chronic condition like sleep apnea. Sleep apnea patients know they should wear that darn CPAP (continuous positive airway pressure) mask they were prescribed, but that doesn't mean they will. Some companies, like Royal Philips, have already shown that digital health can be an effective solution to this problem. But an equally frustrating, an...
Source: MDDI - Category: Medical Devices Authors: Tags: Digital Health Cardiovascular Source Type: news
Abstract Sleep-disordered breathing (SDB) is a risk factor for cardiovascular disease including acute coronary syndrome and acute myocardial infarction, and treating SDB prevents their development and recurrence and improves a patient's prognosis. Therefore, SDB is considered a therapeutic target for cardiovascular disease. In 2010, the Japanese Circulation Society published guidelines for the diagnosis and treatment of SDB in patients with cardiovascular disease. However, therapeutic intervention for patients with SDB was recently reported not to suppress the development or deterioration of cardiovascular disease...
Source: Journal of Nippon Medical School - Category: Universities & Medical Training Authors: Tags: J Nippon Med Sch Source Type: research
(Reuters Health)—Middle-aged women who get poor quality sleep have elevated levels of inflammatory markers, suggesting their risk for heart disease and other illnesses may be increased, U.S. researchers say. Based on sleep monitoring and blood tests of 295 women, most of whom were past menopause, researchers found those who had trouble falling asleep or who... [Read More]
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions Heart Disease postmenopausal postmenopause Sleep sleep apnea Women Source Type: research
Conclusion. Modafinil is a central nervous system stimulant with well-established effectiveness in the treatment of narcolepsy and shift-work sleep disorder. There is conflicting evidence about the benefits of modafinil in the treatment of fatigue and EDS secondary to TBI. One randomized, controlled study states that modafinil does not significantly improve patient wakefulness, while another concludes that modafinil corrects EDS but not fatigue. An observational study provides evidence that modafinil increases alertness in fatigued patients with past medical history of brainstem diencephalic stroke or multiple scleros...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Review excessive daytime sleep fatigue head injury modafinil stroke TBI traumatic brain injury Source Type: research
Authors: Zhang T, Zhang C, Chen RX, Shao B, Liu GA Abstract OBJECTIVE: The purpose of this study was to investigate the relationship of obstructive sleep apnea hypopnea syndrome (OSAHS) with coronary artery lesion quantitative score Syntax Score (SX score) and risk factors for coronary heart disease (CHD). PATIENTS AND METHODS: A total of 115 patients with OSAHS admitted to the Department of Cardiology in our hospital from January 2011 to June 2015 were selected. Philips Respironics Alice 5 Polysomnography was used for sleep monitoring. The patients were divided into mild group (n=32), moderate group (n=36) and...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
To the Editor We read with great interest the article written by Hong et al. They found that prothrombin time in patients with obstructive sleep apnea (OSA) was shorter compared with controls, concluding that OSA might lead to a prothrombotic state, a probable contributing factor to the increase in cardiovascular complications in OSA, including ischemic heart disease and stroke. Observational studies suggest that suppression of apneas by continuous positive airway pressure (CPAP) may improve cardiovascular outcomes. Nevertheless, recent data from a large randomized clinical trial did not prevent cardiovascular events in pa...
Source: JAMA Otolaryngology - Head and Neck Surgery - Category: ENT & OMF Source Type: research
ConclusionsThe methods described in this manuscript propose a medium to high throughput framework for membrane proteome profiling by LC –MS of potential applicability to larger clinical cohorts in a variety of disease contexts.
Source: Clinical Proteomics - Category: Biochemistry Source Type: research
Study Objectives:Obstructive sleep apnea (OSA) and chronic insomnia are two common sleep disorders and both are considered independent risk factors for heart disease. The aim of this study was to investigate the prevalence of comorbid insomnia with OSA and to compare its clinical characteristics with those of OSA without insomnia.Methods:Patients who visited two tertiary university hospital sleep centers were screened. Those with a diagnosis of OSA using polysomnography were divided into two groups based on their scores on the Korean version of the Insomnia Severity Index (ISI-K): OSA with insomnia (OSA+I) (ISI-K score≥...
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
TTP Ventus, UK-based developer of Disc Pump, a tiny, quiet, and very efficient pump, and Sommetrics, US-based creator of aerSleep negative-pressure treatment system for obstructive sleep apnea, teamed up to develop the slimmed-down tetherless aerSlee...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiology Exclusive Medicine Source Type: blogs
R, Gozal D Abstract Obstructive Sleep Apnea (OSA) has emerged as a highly prevalent public health problem that imposes important mid-term and long-term consequences, namely cardiovascular, metabolic, cognitive and cancer-related alterations. OSA is characterized by increased upper airway resistance, alveolar hypoventilation, and recurrent upper airway obstruction during sleep. Recurrent collapse of the upper airway develops with sleep onset, and is associated with both intermittent hypoxemia and sleep fragmentation. The microbiome is a vast and complex polymicrobial ecosystem that coexists with the human organism...
Source: Chest - Category: Respiratory Medicine Authors: Tags: Chest Source Type: research
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