Activation of Nrf2/HO-1 Pathway by Glycogen Synthase Kinase-3 β Inhibition Attenuates Renal Ischemia/Reperfusion Injury in Diabetic Rats
Conclusion: These findings suggest that preconditioning with TDZD-8 may protect the kidney from I/R-induced damage via the activation of the Nrf2/HO-1 pathway in STZ-induced diabetic rats. Further detailed studies are needed to further clarify the underlying mechanisms.Kidney Blood Press Res 2017;42:369 –378
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research