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Optellum unveils lung cancer analysis software

Artificial intelligence software developer Optellum said it will showcase a...Read more on AuntMinnie.com
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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In this study, first we showed significant positive correlation between the expression of ERCCl and vimentin, and significant negative correlation between the ERCCl and E-cadherin in the neoadjuvant chemotherapy group and the simple surgery group. Second, we showed that cisplatin-resistant A549 cells (A549/DDP) acquire EMT phenotype with high expression of drug-resistant proteins, P-gp and ERCC1. Knockdown of TGF-β1 may reverse EMT and significantly reduce the expression of P-gp and ERCC1. Moreover, A549/DDP cells become more sensitive to cisplatin. In summary, our results globally confirm a molecular and phenotypic a...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
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Source: American Journal of Transplantation - Category: Transplant Surgery Authors: Tags: Original Article Source Type: research
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - Category: Biotechnology Authors: Source Type: research
In conclusion, chrysotile induced an imbalanced expression of cancer-related genes in rats' lung tissue. These results contribute to our understanding of the carcinogenic mechanism of chrysotile. PMID: 28905283 [PubMed - as supplied by publisher]
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Tags: Environ Sci Pollut Res Int Source Type: research
In this study, to investigate the involvement of BMMSCs in lymphangiogenesis in lung cancer, and evaluate the inhibitory effect of Jinfukang on the lymphangiogenesis, chimeric mice were prepared by transplanting bone marrow from green fluorescent protein (GFP) transgenic mice (C57BL/6-EGFP) into irradiated C57BL/6 mice. Then, the chimeric mice were injected subcutaneously with freshly prepared Lewis lung carcinoma cell suspension to make lung tumor model, and the model mice were further orally administrated with Jinfukang once per day for 3 weeks. Four weeks after the bone marrow transplantation, GFP-positive cells primari...
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research
An artificial intelligence (AI) algorithm can reliably classify benign and...Read more on AuntMinnie.comRelated Reading: Hybrid modalities disappoint in bone metastases accuracy How to develop deep-learning algorithms for radiology AI can obviate biopsies of indolent thyroid nodules Luminal water MRI could be best for prostate cancer CAD finds vertebral lung cancer metastases
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Authors: Luo D, Deng B, Weng M, Luo Z, Nie X Abstract The outcomes of Lung squamous cell carcinoma (LUSC) is still challenging to evaluate or predict. We aimed to screen prognostic lncRNAs and to mine their roles in LUSC. RNA-Seq data of primary lung cancer were extracted from the Cancer Genome Atlas. Generally, changed lncRNAs in cancer samples were screened and analyzed in univariate survival analysis for identification of prognostic lncRNAs. Robust likelihood-based survival model was generated and random sampling iterations were performed 1000 times to calculate the frequency of feature key lncRNAs. Clustering a...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Authors: Rangaraj S, Venkatachalam R Abstract Silica based organic-inorganic hybrids are turned over the most necessitate biomaterial due to their exotic biomedical properties. Colloidal silica nanoparticles (SNPs) of high surface area are synthesized from the bamboo wastes (leave biomass) as a viable and promising alternative to synthetic silica sol through alkaline extraction process. Physico-chemical properties of the prepared silica powders are examined employing extensive characterization tools. The characteristic results of the silica sol demonstrate amorphous particles (average size: 25 nm) with relat...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - Category: Biotechnology Authors: Source Type: research
Modulation of T-cell activity through blockade of coinhibitory molecules has revolutionized the treatment of various malignancies. Several immune checkpoint inhibitors are currently Food and Drug Administration approved which target various coinhibitory pathways including cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), programmed death 1 receptor (PD-1), and programmed cell death ligand-1. Clinical trials that lead to the Food and Drug Administration approval of these agents often excluded patients with an organ transplant. Excluding these patients was deliberate due to concern that immune checkpoint inhibitor therap...
Source: Journal of Immunotherapy - Category: Allergy & Immunology Tags: Review Article Source Type: research
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