Is a new flu pandemic just three mutations away?

Conclusion This laboratory study analysed an H7N9 strain of bird flu. Researchers wanted to explore whether a particular change to the surface proteins of a virus was capable of allowing the strain to bind to human tissue. This would theoretically lead to human-to-human transmission of the flu virus. It is worth noting that this ability to attach to human cells does not necessarily mean a mutated bird flu virus will be able to infect, replicate and transmit between humans. Other changes would also be required. However, they were unable to further investigate whether this surface change could lead to human-to-human transmission of the virus because this type of experiment is not permitted under US law. This research attracted the attention of several experts in the field. Dr Fiona Culley, spokesperson for the British Society for Immunology, &Senior Lecturer in Respiratory Immunology at Imperial College London commented: "This is a good, thorough study which specifically aimed to identify which changes in bird flu would allow the virus to attach to human cells." "The authors found that certain combinations of three mutations were needed for the bird flu to be able to attach to human lung cells. They could potentially happen, but there is currently no evidence that they have ever occurred and the chances of all three occurring together is relatively low." Links To The Headlines Just THREE mutations are needed to make bird flu a potential pandemic strain ...
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Medical practice Source Type: news

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Publication date: Available online 12 December 2018Source: Social Science &MedicineAuthor(s): Amelia M. Jamison, Sandra Crouse Quinn, Vicki S. FreimuthAbstractVaccine confidence depends on trust in vaccines as products and trust in the system that produces them. In the US, this system consists of a complex network connecting pharmaceutical companies, government agencies, and the healthcare system. We explore narratives from White and African American adults describing their trust in these institutions, with a focus on influenza vaccine. Our data were collected between 2012 and 2014 as part of a mixed-methods investigat...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
No abstract available
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Current Abstracts Source Type: research
China's agriculture ministry said on Wednesday two new African swine fever outbreaks were confirmed in Sichuan and Qinghai provinces.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
The outbreak of the Ebola virus in recent years has resulted in numerous research initiatives to seek new solutions to contain the virus. A number of approaches that have been investigated include new vaccines to boost the immune system. An alternative post-exposure treatment is presented in this paper. The proposed approach for clearing the Ebola virus can be developed through a microfluidic attenuator, which contains the engineered bacteria that traps Ebola flowing through the blood onto its membrane. The paper presents the analysis of the chemical binding force between the virus and a genetically engineered bacterium co...
Source: IEEE/ACM Transactions on Computational Biology and Bioinformatics - Category: Bioinformatics Source Type: research
Publication date: Available online 10 December 2018Source: Veterinary MicrobiologyAuthor(s): Dezhi Li, Fang Tang, Feng Xue, Jianluan Ren, Yun Liu, Dehong Yang, Jianjun Dai
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
(Photo by rawpixel on Unsplash) Olympus (TYO:7733) and a former senior executive in Japan have pleaded guilty in Newark, N.J., to failing to file required adverse event reports involving infections connected to duodenoscopes, and to continuing to sell the devices in the United States despite those failures, the Justice Department announced.   Tokyo-based Olympus and Hisao Yabe, 62, both entered guilty pleas before U.S. District Court Judge Stanley Chesler in Newark Federal Court: Olympus to three counts, and Yabe to one count, of distributing misbranded medical devices in interstate commerce in violatio...
Source: Mass Device - Category: Medical Devices Authors: Tags: Blog Business/Financial News Food & Drug Administration (FDA) Legal News Olympus Source Type: news
ConclusionsFESR has a great potential for the treatment of ALI induced by IAV and the underlying action mechanism might be closely associated with antiviral, anti-inflammatory and anti-complementary properties. Furthermore, FESR resulted in more potent therapeutic effect than BG in the treatment of IAV-induced ALI.Graphical Abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
[New Era] Windhoek -The Ministry of Health and Social Services (MOHSS) is undertaking a rapid assessment survey on knowledge, attitude, and practices of residents of Havana and Goreangab informal settlements on Hepatitis E virus during the ongoing outbreak.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
[New Era] Windhoek -More than a year since Namibia experienced Hepatitis E, which led to it being declared an outbreak last December, health officials and relevant stakeholders are called for the redoubling of efforts to contain the disease.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
[New Era] Windhoek -The World Health Organisation (WHO) has since the outbreak of Hepatitis E committed N$3 million to support the Ministry of Health and Social Services (MOHSS) to intensify efforts in the response against the disease.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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