Diabetic nephropathy: Glucose metabolic flux in DN

Nature Reviews Nephrology 13, 384 (2017). doi:10.1038/nrneph.2017.70 Author: Susan J. Allison Diabetic nephropathy (DN) is a common cause of end-stage renal disease and is thought to be caused, at least in part, by hyperglycaemia-induced mitochondrial dysfunction. New research shows that activation of pyruvate kinase M2 (PKM2) can protect podocytes from glucose-induced damage by increasing glucose metabolic
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research