Effects of dexmedetomidine on CD42a+/CD14+, HLADR+/CD14+ and inflammatory cytokine levels in patients undergoing multilevel spinal fusion

Multi segmental spinal fusion is characterized by severe trauma and stress that frequently affect middle aged and elderly people. Surgery as well as anesthesia has been shown to modulate the stress response which involves both the endocrine as well as immune system [1]. Meanwhile, excessive inflammatory reactions lead to an imbalance of body function, causing serious adverse reactions. Therefore, excessive inflammatory response in the perioperative period is an important factor influencing the prognosis of patients.
Source: Clinical Neurology and Neurosurgery - Category: Neurosurgery Authors: Source Type: research