The Time is Now to Move Far Beyond the Pill

There has been a lot of talk about ‘beyond the pill'strategies for many years, as companies create services and solutions that are complementary to their drugs. More recently, with the many changes affecting healthcare, pharma companies are adjusting their business models and looking at strategies to improve patient outcomes and diversify revenue sources that go far beyond the pill.Wellness programs and chronic disease management are common approaches, offering opportunities for companies to increase customer engagement leading to improved outcomes. For example, Biogen has used Fitbits to monitor the walking activity of patients with multiple sclerosis, previously only measured during visits to the doctor ’s office.This is a good example of an integrated solution that help patients achieve better health outcomes by engaging them with the process. Tracking their own progress – and seeing what other patients are doing – can build community and encouragement. Such communication is especially important in chronic long-term conditions where patient engagement is critical for improved outcomes.Wearables, ingestables, and implantables offer many new opportunities for pharma companies to become involved in the overall health of their customers, as well as to know how well their medicines are working. As technology becomes a bigger part of pharma, it's likely that medications will have an accompanying mobile app, with devices to track a drug's outcome.Leadershi...
Source: EyeForPharma - Category: Pharmaceuticals Authors: Source Type: news

Related Links:

Abstract Dendritic cells (DCs) play a key role not only in the initiation of primary immune responses, but also in the development and maintenance of immune tolerance. Numerous protocols have been developed to generate tolerogenic DCs (tolDCs) ex vivo, and the therapeutic efficacy of ex vivo-generated tolDCs has been demonstrated in autoimmune disease animal models. Based on successes in small animal models, several clinical trials have been completed or are on-going in patients with autoimmune diseases such as rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and Crohn's disease. Here we describe the met...
Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
AbstractMany  central nervous system diseases currently lack effective treatment and are often associated with defects in microvascular function, including a failure to match the energy supplied by the blood to the energy used on neuronal computation, or a breakdown of the blood–brain barrier. Pericytes, an u nder-studied cell type located on capillaries, are of crucial importance in regulating diverse microvascular functions, such as angiogenesis, the blood–brain barrier, capillary blood flow and the movement of immune cells into the brain. They also form part of the “glial” scar isolating dam...
Source: Acta Neuropathologica - Category: Neurology Source Type: research
Publication date: August 2018Source: The Lancet Neurology, Volume 17, Issue 8Author(s): Martin Steinhoff, Martin Schmelz, Imre LÅ‘rinc Szabó, Anne Louise OaklanderSummaryUnlike conventional itch, neuropathic itch develops in normal skin from excess peripheral firing or dampened central inhibition of itch pathway neurons. Neuropathic itch is a symptom of the same central and peripheral nervous system disorders that cause neuropathic pain, such as sensory polyneuropathy, radiculopathy, herpes zoster, stroke, or multiple sclerosis, and lesion location affects symptoms more than aetiology. The causes of neuropathic itch...
Source: The Lancet Neurology - Category: Neurology Source Type: research
In the first 10 days of July, at least 10 drugmakers and biotechnology companies raised prices on at least 20 brand-name medicines, a review of pricing data from Rx Savings Solutions and Bloomberg Intelligence shows. The increases, for medications for cancer, diabetes, multiple sclerosis, and liver disease, were generally each less than 10 percent. But the price of one little-prescribed sleep aid was raised by more than 700 percent. (Robert Langreth and Cynthia Koons, Bloomberg News)        
Source: The Commonwealth Fund: Publications - Category: International Medicine & Public Health Source Type: research
A new study has raised the possibility that stress may cause autoimmune disease, such as lupus or rheumatoid arthritis, because it found a higher incidence of autoimmune diseases among people who were previously diagnosed with stress-related disorders. I have patients who heard about this research and are saying, “I knew it!” But before we accept a potential link between stress and autoimmune disease, let’s look at some details of the study and consider how we define the terms “autoimmune disease,” “stress,” and “stress-related disorder.” What is autoimmune disease? The...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Autoimmune diseases Health Stress Source Type: blogs
ConclusionCardiovascular conditions are as common in those with demyelinating diseases compared to unaffected individuals, with hypertension being more common among those with MS.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: July 2018Source: Multiple Sclerosis and Related Disorders, Volume 23Author(s): Simon B.N. Thompson, Alister Coleman, Nicola WilliamsAbstractYawning is a significant behavioural response and, together with cortisol, is potentially a new diagnostic marker of neurological diseases. Evidence of an association between yawning and cortisol was found which supports the Thompson Cortisol Hypothesis and thermoregulation hypotheses, indication that brain cooling occurs when yawning. 117 volunteers aged 18–69 years were randomly allocated to experimentally controlled conditions to provoke yawning. Thirty-three...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: July 2018Source: Autoimmunity Reviews, Volume 17, Issue 7Author(s): Lin-Chong Su, Xiao-Yan Liu, An-Fang Huang, Wang-Dong XuAbstractInterleukin 35 (IL-35) is the recently identified member of the IL-12 family of cytokines and provides the possibility to be a target for new therapies for autoimmune, inflammatory diseases. It is composed of an α chain (p35) and a β chain (EBI3). IL-35 mediates signaling by binding to its receptors, activates subsequent signaling pathways, and therefore, regulates the differentiation, function of T, B cells, macrophages, dendritic cells. Recent findings have shown ...
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
Publication date: July 2018Source: Multiple Sclerosis and Related Disorders, Volume 23Author(s): Simon B.N. Thompson, Alister Coleman, Nicola WilliamsAbstractYawning is a significant behavioural response and, together with cortisol, is potentially a new diagnostic marker of neurological diseases. Evidence of an association between yawning and cortisol was found which supports the Thompson Cortisol Hypothesis and thermoregulation hypotheses, indication that brain cooling occurs when yawning. 117 volunteers aged 18–69 years were randomly allocated to experimentally controlled conditions to provoke yawning. Thirty-three...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: July 2018Source: Autoimmunity Reviews, Volume 17, Issue 7Author(s): Lin-Chong Su, Xiao-Yan Liu, An-Fang Huang, Wang-Dong XuAbstractInterleukin 35 (IL-35) is the recently identified member of the IL-12 family of cytokines and provides the possibility to be a target for new therapies for autoimmune, inflammatory diseases. It is composed of an α chain (p35) and a β chain (EBI3). IL-35 mediates signaling by binding to its receptors, activates subsequent signaling pathways, and therefore, regulates the differentiation, function of T, B cells, macrophages, dendritic cells. Recent findings have shown ...
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
More News: Clinical Trials | Diabetes | Diovan | Endocrinology | Environmental Health | Eyes | Hospitals | Lung Transplant | Multiple Sclerosis | Partnerships | Pediatrics | Pharmaceuticals | Study | Transplant Surgery | Transplants