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Untreated Sleep Apnea May Worsen Markers Of Heart Health and Diabetes Untreated Sleep Apnea May Worsen Markers Of Heart Health and Diabetes

Properly treating obstructive sleep apnea (OSA) may have benefits for the heart and for blood sugar, a new study suggests.Reuters Health Information
Source: Medscape Pathology Headlines - Category: Pathology Tags: Family Medicine/Primary Care News Source Type: news

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Authors: Mutlu LC, Tülübaş F, Alp R, Kaplan G, Yildiz ZD, Gürel A Abstract OBJECTIVE: Obstructive sleep apnea syndrome (OSAS) has been associated with elevated biochemical markers of inflammation. Although the exact mechanism is unknown, both sleep deprivation and hypoxemia are believed to be important causative factors. YKL-40, also known as chitinase-like protein, has been shown to be related to various inflammatory conditions including atherosclerosis, diabetes, cancer, and asthma. The present study aimed to evaluate the relationship between YKL-40 levels and the Apnea Hypopnea Index (AHI) in pat...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Obstructive sleep apnea (OSA) is a highly prevalent condition that is associated with excessive daytime sleepiness, reduced quality of life, hypertension, and increased cardiovascular risk.[1] Patients with type 2 diabetes are at particularly high risk for OSA. The Sleep Heart Health Study, a community-based cohort study, observed a 58% prevalence of OSA among participants with type 2 diabetes. Similarly, in a subset of overweight and obese diabetics participating in the LookAHEAD trial, the prevalence of OSA was over 86%.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
ConclusionsOver one third of U.S. adults have obesity. Obesity is associated with a range of comorbidities, including diabetes, cardiovascular disease, obstructive sleep apnea, and cancer; however, modest weight loss in the 5%–10% range, and above, can significantly improve health‐related outcomes. Many individuals struggle to maintain weight loss, although strategies such as realistic goal‐setting and increased consultation frequency can greatly improve the success of weight‐management programs. Nurse practitioners have key roles in establishing weight‐loss targets, providing motivation and support, and impl...
Source: Journal of the American Academy of Nurse Practitioners - Category: Nursing Authors: Tags: SUPPLEMENTS ‐ SPONSORED Source Type: research
A 41-year-old Caucasian female with a history of non-traumatic fractures was referred to an endocrinologist for further evaluation. She was reported to have generalized weakness, stress fractures of the lower limbs, and multiple non-traumatic rib fractures within the past year. Her significant past medical history includes: vertebral compression fractures status post lumbar fusion, type 2 diabetes mellitus, obstructive sleep apnea and morbid obesity, for which she underwent sleeve gastrectomy several years ago.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Clinical Communication to the Editor Source Type: research
The FDA has granted Respicardia, a company out of Minnetonka, Minnesota, approval to introduce its Remedē implantable sleep apnea treatment system. The Remedē treats sleep apnea by stimulating one of the phrenic nerves that regulates the activity of the diaphragm. People with central sleep apnea exhibit shallow breaths and/or pauses in breathing that can have a terrible effect on their sleep quality and, as it turns out, their overall cardiovascular health, and increase their chances for obesity and diabetes. The poor control of the diaphragm in such patients is caused by the brain sending improper si...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiology Medicine Radiology Source Type: blogs
Conclusions:The study reported high rates of readmission and ED visits, thus the effectiveness of different types of weight loss surgeries should be further evaluated, particularly in individuals with complicated medical issues such as diabetes, dyslipidemia, and obstructive sleep apnea.Obes Facts 2017;10:432-443
Source: Obesity Facts - Category: Eating Disorders & Weight Management Source Type: research
Conclusion Renal impairment is common in OSAS patients but more frequent if associated with diabetes mellitus. RDW% can be used as simple screening test for early detection of renal injury in OSAS patients with or without diabetes mellitus.
Source: Egyptian Journal of Chest Diseases and Tuberculosis - Category: Respiratory Medicine Source Type: research
is a complex multifactorial metabolic disorder that extends beyond glucose control. Current studies have found that microvascular disease (neuropathy, nephropathy, and retinopathy), macrovascular disease (stroke, coronary artery disease, and peripheral vascular disease), periodontal disease, cognitive dysfunction, blood pressure changes, obstructive sleep apnea, low testosterone level, fatty liver disease, and cancer are some of conditions that are present with the onset of glycemic dysregulation. The presence of prediabetes increases the risk of developing type 2 diabetes 3-fold to 10-fold. The identification and treatme...
Source: Nursing Clinics of North America - Category: Nursing Authors: Source Type: research
CONCLUSIONS: OSA is associated with STDR in patients with type 2 diabetes. OSA is an independent predictor for the progression to preproliferative/proliferative DR. Continuous positive airway pressure treatment was associated with reduction in preproliferative/proliferative DR. Interventional studies are needed to assess the impact of OSA treatment on STDR. PMID: 28594570 [PubMed - indexed for MEDLINE]
Source: Am J Respir Crit Car... - Category: Intensive Care Authors: Tags: Am J Respir Crit Care Med Source Type: research
Obstructive sleep apnea (OSA) is common, and many cross-sectional and longitudinal studies have established OSA as an independent risk factor for the development of a variety of adverse metabolic disease states, including hypertension, insulin resistance, type 2 diabetes, nonalcoholic fatty liver disease, dyslipidemia, and atherosclerosis. Nasal continuous positive airway pressure (CPAP) has long been the mainstay of therapy for OSA, but definitive studies demonstrating the efficacy of CPAP in improving metabolic outcomes, or in reducing incident disease burden, are lacking; moreover, CPAP has variable rates of adherence.
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Source Type: research
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