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Abdominal X-rays Decreased in Children With Constipation Abdominal X-rays Decreased in Children With Constipation

A simple, cost-effective intervention decreased rates of unnecessary abdominal X-rays in children seen in the ED for constipation, a new study has found.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Emergency Medicine News Source Type: news

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Abstract: Opioid-induced constipation has a negative impact on quality of life for patients with chronic pain and can affect more than a third of patients. A related but separate entity is postoperative ileus, which is an abnormal pattern of gastrointestinal motility after surgery. Nonselective μ-opioid receptor antagonists reverse constipation and opioid-induced ileus but cross the blood-brain barrier and may reverse analgesia. Peripherally acting μ-opioid receptor antagonists target the μ-opioid receptor without reversing analgesia. Three such agents are US Food and Drug Administration approved. We reviewed the ...
Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: Chronic and Interventional Pain: Review Article Source Type: research
Conditions:   Fecal Incontinence;   Constipation Intervention:   Device: Fecobionics Sponsor:   Giome Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Abstract Naloxegol is a peripherally acting μ-opioid receptor antagonist that was developed for the treatment of opioid-induced constipation. Modeling and simulation of naloxegol efficacy and tolerability informed selection of doses for phase III studies and provided comprehensive dosage recommendations for the naloxegol US package insert. PMID: 28548207 [PubMed - indexed for MEDLINE]
Source: Clinical Pharmacology and Therapeutics - Category: Drugs & Pharmacology Authors: Tags: Clin Pharmacol Ther Source Type: research
Publication date: Available online 20 October 2017 Source:IDCases Author(s): Itaru Nakamura, Kenji Yagi, Takashi Kumagai, Nobuo Ohta The rise in eco-tourism and travel off the beaten track have increased numbers of tourists with schistosomiasis which is seldom seen in developed countries, although this disease is considered a neglected tropical disease especially in poor communities. A Guinean male living in Japan was seen complaining of severe constipation. He was positive for fecal occult blood (FOB) and underwent colonoscopy. Colonoscopy showed petechiae of the rectal mucosa, with pathologic examination of biopsy tissu...
Source: IDCases - Category: Infectious Diseases Source Type: research
Conditions:   Constipation;   Constipation Drug Induced Interventions:   Drug: Naloxegol 25 MG;   Other: Placebo pill Sponsor:   Angela Fellner Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Liu P, Wei H, Chang J, Miao G, Liu X, Li Z, Liu L, Zhang X, Liu C Abstract Rhubarb is commonly used to treat constipation in China and anthraquinones (AQs) are the active components present in rhubarb. However, an increasing number of studies have reported that AQs induce nephrotoxicity. In the present study, rhubarb total free anthraquinones (RTFA) oral colon-specific drug delivery granules (RTFA-OCDD-GN) were prepared to determine whether RTFA-OCDD-GN could reduce the nephrotoxicity that occurs when AQs produce purgative efficacy. RTFA-OCDD-GN were prepared using pH-enzyme double-layer coating technology...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
This study examined possible clinical factors associated with the symptoms of constipation in patients with DM. MethodsThis was a multicenter study. Participants were consecutive Japanese patients undergoing treatment for type 1 or type 2 DM. Constipation was evaluated using the gastrointestinal symptom rating scale. Diabetic neuropathy was evaluated by the presence or absence of peripheral neuropathy of the lower limbs. ResultsOf 419 participants, 258 were men and 161 women (ratio: 1.6:1), with a mean age of 63.6 ± 12.5 years. In multivariate analysis, symptoms of constipation were significantly associated with age...
Source: Journal of Gastroenterology and Hepatology - Category: Gastroenterology Authors: Tags: Gastroenterology Source Type: research
As a primary care doctor, I see a lot of women dealing with the inconvenience, discomfort, and embarrassment of urinary incontinence (unintended leaking of urine). Some are comfortable bringing this up right away. Others suffer needlessly because they feel too shy or awkward to mention it. The truth is, an estimated 45% of women experience some form of urinary incontinence at some point in their lives. That’s almost half of all women! It’s a very big deal. Urinary incontinence can negatively affect physical and emotional well-being. For example, women may avoid going out because they’re worried about havi...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Kidney and urinary tract Women's Health Source Type: blogs
A three-year-old boy was recently referred from another institution to our department for a left-sided cervical mass. The mass was incidentally discovered when the boy was 6 months old. The cervical mass had grown slowly and the boy was otherwise asymptomatic. He had no symptoms of fever, vomiting, diarrhea, constipation, or recent weight changes, according to his parents. His past medical history was unremarkable and there was no reported recent radiation exposure or trauma. The child's mother had a full-term and uncomplicated pregnancy.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Tags: Clinicopathologic Conference Source Type: research
Title: Trouble With Constipation? One Simple Step May HelpCategory: Health NewsCreated: 10/16/2017 12:00:00 AMLast Editorial Review: 10/17/2017 12:00:00 AM
Source: MedicineNet Digestion General - Category: Nutrition Source Type: news
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