Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia

Conclusions:
Phonologic loop dysfunction is a central feature of AD-associated PPA and specifically correlates with temporoparietal neurodegeneration. Quantitative measures of phonologic loop function, combined with modified clinical lvPPA criteria, may help discriminate AD-associated PPA.

Source: Neurology - June 12, 2017 Category: Neurology Authors: Giannini, L. A. A., Irwin, D. J., McMillan, C. T., Ash, S., Rascovsky, K., Wolk, D. A., Van Deerlin, V. M., Lee, E. B., Trojanowski, J. Q., Grossman, M. Tags: Alzheimer's disease, Dementia aphasia, Assessment of cognitive disorders/dementia ARTICLE Source Type: research