No histologic evidence of foetal cardiotoxicity following exposure to maternal hydroxychloroquine.

No histologic evidence of foetal cardiotoxicity following exposure to maternal hydroxychloroquine.
Clin Exp Rheumatol. 2017 Jun 06;
Authors: Friedman D, Lovig L, Halushka M, Clancy RM, Izmirly PM, Buyon JP
Abstract
It is currently recommended that hydroxychloroquine (HCQ) be maintained during pregnancy in patients with systemic lupus erythematosus. Recent data suggest that this Toll-like receptor inhibitor may also reduce the recurrence rate of anti-SSA/Ro associated congenital heart block (CHB). This case report describes a unique situation in which a CHB-afflicted, HCQ-exposed pregnancy was electively terminated. The heart did not reveal any characteristic features of cardiotoxicity, providing further evidence supporting the safety of foetal exposure to HCQ.
PMID: 28598777 [PubMed - as supplied by publisher]

Source: Clinical and Experimental Rheumatology - June 11, 2017 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research