Polymorphism rs2073618 of the osteoprotegerin gene as a potential marker of subclinical carotid atherosclerosis in Caucasians with type 2 diabetes mellitus.

CONCLUSIONS: Despite the fact that OPG rs2073618 genotypes failed to predict the serum OPG levels as there was no statistical difference among compared genotypes, our results demonstrate that the rs2073618 polymorphism could be a possible genetic marker for the prediction of increased risk for carotid plaque burden as a measure of advanced subclinical atherosclerosis in T2DM subjects.
PMID: 28593808 [PubMed - as supplied by publisher]

Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 8, 2017 Category: Surgery Authors: Pleskovič A, Ramuš SM, Pražnikar ZJ, Šantl Letonja M, Vujkovac AC, Gazdikova K, Caprnda M, Gaspar L, Kruzliak P, Petrovič D Tags: Vasa Source Type: research