AbbVie must pay $15 million in Depakote birth-defect trial: jury

(Reuters) - A federal jury on Friday awarded $15 million to a 10-year-old boy whose mother blamed his birth defect on AbbVie Inc's bipolar disorder drug Depakote that she took while pregnant, in the latest trial among hundreds of lawsuits over the product.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

Related Links:

Offering increasing financial incentives to patients recently prescribed antidepressants may increase the likelihood they take the medication as prescribed, suggests areport inJAMA Psychiatry. The pilot study also found patients who received the financial incentives over six weeks were more likely to report improvements in depression symptoms compared with those who received antidepressants only.For the study, Steven C. Marcus, Ph.D., of the University of Pennsylvania School of Social Policy and Practice and colleagues enrolled 120 patients aged 21 to 64 with depression (Patient Health Questionnaire-9 [PHQ-9] score of 10 o...
Source: Psychiatr News - Category: Psychiatry Tags: antidepressants depression financial incentives JAMA Psychiatry medication adherence PHQ-9 remission response Source Type: research
In conclusion, it remains unclear if brain-specific regional and temporal changes occur in the expression of the different APP variants during AD progression. Since APP is also found in blood cells, assessing the changes in APP mRNA expression in peripheral blood cells from AD patients has been considering an alternative. However, again the quantification of APP mRNA in peripheral blood cells has generated controversial results. Brain APP protein has been analyzed in only a few studies, probably as it is difficult to interpret the complex pattern of APP variants and fragments. We previously characterized the soluabl...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
ConclusionTaken together, there was strong evidence for a small (RR  
Source: Social Psychiatry and Psychiatric Epidemiology - Category: Psychiatry Source Type: research
Although lithium is widely used as a first-line treatment for mood disorders, its mood-stabilizing effects remain not fully understood. A growing body of data are stressing that lithium seems to show broader properties, including neuroprotective effects. Lithium's ability to inhibit glycogen synthase kinase 3β, an enzyme that participates in the phosphorylation of τ, a microtubule-associated protein, stimulated interest in its possible therapeutic role in Alzheimer disease and other neurodegenerative disorders. Preliminary data also support exploration of lithium's potential therapeutic role in multiple sclerosis,...
Source: Clinical Neuropharmacology - Category: Neurology Tags: Case Reports Source Type: research
  Take the bull by the horns! Pick yourself up by your bootstraps! Are these cliches condescending for people with mental illness? Or is there a grain of truth to them? Today, Gabe and Lisa debate the pros and cons of the all too common “taking your life back” advice we all get from well-meaning people. Gabe shares his personal story of gaining back control of his life a day at a time while healing from depression. When you struggle with mental illness, how much of your behavior, thoughts and emotions do you actually have control over? Is it helpful to feel in control of your life, even when it screws you...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Mental Health and Wellness Not Crazy Podcast Self-Help Source Type: blogs
Women who take medication for anxiety, depression or other behavioral health conditions worry about whether they’ll need to discontinue use when they conceive. For years, well-intentioned care providers believed this to be the only clinically responsible solution. The reason for this was simple: because it’s considered unethical to test medication on pregnant and nursing mothers, there was no literature to provide evidence for safety.  But we’ve come a long way, and the field of perinatal psychiatry has evolved a great deal. We now have evidence that supports the safety and efficacy of certain medic...
Source: Cord Blood News - Category: Perinatology & Neonatology Authors: Tags: Cord Blood Cord Tissue Source Type: blogs
AbstractKey content Multifetal pregnancy reduction (MFPR) and selective termination (ST) are conceptually different procedures. Essential prerequisites for delivering these interventions are detailed counselling, multidisciplinary input within a tertiary fetal medicine service, careful choice of operative technique and appropriate gestational age, depending on the type of pregnancy and indication. Operative techniques that may be used are chemical, thermal, radiofrequency and laser, depending on chorionicity as well as other factors. Intracardiac KCl is appropriate when there is independent chorionicity and carries a lowe...
Source: The Obstetrician and Gynaecologist - Category: OBGYN Authors: Tags: REVIEWS Source Type: research
Does religion help or harm people with severe mental illness? In today’s Not Crazy podcast, Gabe and Lisa welcome Rachel Star Wither, host of the Inside Schizophrenia podcast, to discuss religion’s role (or lack thereof) in treating those struggling with schizophrenia or bipolar disorder. Rachel relates her personal experiences of mixing religion with her illness and shares how she currently manages to believe in God while keeping her faith “separate” from her symptoms. Tune in for a deep discussion on religion and severe mental illness, including Rachel’s 3-day exorcism experience at age 17....
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Disorders General Interview Not Crazy Podcast Schizophrenia Spirituality Source Type: blogs
CONCLUSIONS: Prescription of valproate to women of childbearing age in our sample currently falls well short of best practice. Urgent action at both clinician and organisational levels is required to address this risk. PMID: 32586113 [PubMed - as supplied by publisher]
Source: Australasian Psychiatry - Category: Psychiatry Authors: Tags: Australas Psychiatry Source Type: research
Authors: Konstantinou G, Spyropoulou A, Zervas I Abstract Postpartum depression is a debilitating mental disorder with a high prevalence, usually related with a past psychiatric history of major depressive disorder, postpartum depression, bipolar disorder, premenstrual syndrome (PMS), and perinatal depressive symptoms during gestation. However, the existing literature does not sufficiently elucidate the pathophysiology of this clinical entity which appears in such a crucial period of woman's life. This review aims to search the available data regarding the involvement of immunological and autoimmune mechanisms in i...
Source: Psychiatriki - Category: Psychiatry Tags: Psychiatriki Source Type: research
More News: Bipolar | Divalproex Sodium | Health | Lawsuits | Legislation | Mania | Pregnancy