Malignant hyperthermia susceptibility in patients with exertional rhabdomyolysis: a retrospective cohort study and updated systematic review

ConclusionFindings from the Canadian patient cohort and the systematic review all signal a potential association between MH susceptibility and ER. The presence of MH-causative mutations and putative deleteriousRYR1 variants in ER patients without a history of adverse anesthetic reactions suggests their possible increased risk for MH.

http://link.springer.com/10.1007/s12630-017-0865-5

Source: Canadian Journal of Anesthesia - June 9, 2017 Category: Anesthesiology Source Type: research