PFO Closure for Cryptogenic Stroke: A Review and Clinical Treatment Algorithm

We describe the historical context of PFO closure and review the observational and randomized control trial evidence in this field, culminating in the recent Food and Drug Administration approval of the first dedicated closure device for PFO. Guidelines and consensus statements are discussed, and a novel treatment algorithm is proposed. Future directions in PFO closure will include new devices, further data from completed and upcoming clinical trials, and potential expansion into other disease states associated with PFO.
Source: Cardiology in Review - Category: Cardiology Tags: Review Articles Source Type: research