Celiac Disease Tests Do Not Reflect Ongoing Mucosal Damage Celiac Disease Tests Do Not Reflect Ongoing Mucosal Damage

Tests for serum transglutaminase (tTG) and endomysial antibodies (EMA) fail to detect persistent villous atrophy in many patients with celiac disease on gluten-free diets, according to a meta-analysis.Reuters Health Information
Source: Medscape Pathology Headlines - Category: Pathology Tags: Gastroenterology News Source Type: news

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Condition:   Celiac Disease Interventions:   Drug: TIMP-GLIA;   Drug: Placebo Sponsor:   COUR Pharmaceutical Development Company, Inc. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: These outcomes may be due to the low bone density of patients with CD. A controlled trial conducted using a larger sample is needed to support and extend these data. PMID: 30402878 [PubMed - as supplied by publisher]
Source: Folia Morphologica - Category: Anatomy Tags: Folia Morphol (Warsz) Source Type: research
(MedPage Today) -- Health news and commentary from around the Web gathered by the MedPage Today staff
Source: MedPage Today Psychiatry - Category: Psychiatry Source Type: news
In conclusion, celiac disease, isolated and even more when associated with HT, determines a peculiar behavior of Breg cells which are increased in number but possibly functionally defective. Furthermore, the association CD + HT was characterized by a reduction of Breg memory subsets as compared with the isolated disorders. The behavior of Th17 subset in patients with celiac disease associated with HT might have been sensitive to the effect of long-lasting GFD, and it is essentially determined by the presence of thyroid autoimmunity. PMID: 30402096 [PubMed]
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
ConclusionWe found a point prevalence of CD close to previous described prevalence in the general population of Swedish children. Therefore, general screening for CD in children with JIA is not supported by our data. However, this study shows that asymptomatic CD in children with JIA may be found by screening.
Source: Acta Paediatrica - Category: Pediatrics Authors: Tags: Regular Article Source Type: research
If you're suffering from intestinal upset, you might be tempted to eliminate gluten from your diet. Many people follow gluten-free diets not because they have celiac disease, an autoimmune condition triggered by sensitivity to the grain component, but because they think avoiding it improves their digestive health. But experts say that gluten is likely not the culprit giving people gas and diarr hea — it's another food component called fructans, The Washington Post reports. The number of Americans…
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
The treatment, Nexvax2, is currently in a phase 2 clinical trial in Australia.
Source: ABC News: Health - Category: Consumer Health News Tags: GMA Source Type: news
The treatment, Nexvax2, is currently in a phase 2 clinical trial in Australia.
Source: ABC News: Health - Category: Consumer Health News Tags: GMA Source Type: news
Endosc Int Open 2018; 06: E1369-E1378 DOI: 10.1055/a-0732-5060 Background and study aims Although duodenal biopsy is considered the “gold standard” for diagnosis of celiac disease, the optimal location of biopsy within the small bowel for diagnosis remains unclear. The primary aim of this study was to perform a structured systematic review and meta-analysis to evaluate the diagnostic utility of endoscopic duodenal bulb biopsy for celiac disease. Patients and methods Searches of PubMed, EMBASE, Web of Science, and Cochrane Library databases were performed from 2000 through December 2017. Review o...
Source: Endoscopy International Open - Category: Gastroenterology Authors: Tags: Original article Source Type: research
Condition:   Celiac Disease Intervention:   Sponsor:   Tazeen Rasheed Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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