Role of habenula and amygdala dysfunction in Parkinson disease patients with punding

Conclusions:
A breakdown of the connectivity among the crucial nodes of the reward circuit (i.e., habenula, amygdala, basal ganglia, frontal cortex) might be a contributory factor to punding in PD. This study provides potential instruments to detect and monitor punding in patients with PD.

Source: Neurology - June 5, 2017 Category: Neurology Authors: Markovic, V., Agosta, F., Canu, E., Inuggi, A., Petrovic, I., Stankovic, I., Imperiale, F., Stojkovic, T., Kostic, V. S., Filippi, M. Tags: MRI, fMRI, Parkinson's disease/Parkinsonism, All Psychiatric disorders ARTICLE Source Type: research