HLA-A*24:02 as a common risk factor for antiepileptic drug-induced cutaneous adverse reactions

Conclusions:
HLA-A*24:02 is a common genetic risk factor for cutaneous adverse reactions induced by aromatic antiepileptic drugs in the southern Han Chinese and possibly other ethnic populations. Pretreatment screening is recommended for people in southern China.

Source: Neurology - June 5, 2017 Category: Neurology Authors: Shi, Y.-W., Min, F.-L., Zhou, D., Qin, B., Wang, J., Hu, F.-Y., Cheung, Y.-K., Zhou, J.-H., Hu, X.-S., Zhou, J.-Q., Zhou, L.-M., Zheng, Z.-z., Pan, J., He, N., Liu, Z.-S., Hou, Y.-Q., Lim, K.-S., Ou, Y.-m., Hui-Ping Khor, A., Ng, C.-C., Mao, B.-J., Liu, X Tags: All Toxicology, Patient safety, Case control studies, Antiepileptic drugs, All Genetics ARTICLE Source Type: research