Prognostic value of MGMT protein expression in glioblastoma excluding non ‐tumour cells from the analysis

ConclusionOur data indicate that MGMT protein expression in tumour cells has an independent prognostic significance. Exclusion of non‐tumour cells contributed to a more exact analysis of tumour‐specific MGMT protein expression. This should be incorporated in future studies evaluating MGMT status before potential integration into clinical practice.This article is protected by copyright. All rights reserved.

Source: Neuropathology and Applied Neurobiology - June 1, 2017 Category: Neurology Authors: Rikke H. Dahlrot, Joseph Dowsett, Sigurd Fosmark, Annika Malmstr öm, Roger Henriksson, Henning Boldt, Karin Stricker, Mia D. Sørensen, Hans S. Poulsen, Malgorzata Lysiak, Peter Söderkvist, Johan Rosell, Steinbjørn Hansen, Bjarne W. Kristensen Tags: Original Article Source Type: research