Variation in the Viral Hepatitis and HIV Policies and Practices of Methadone Maintenance Programs

Conclusions: Despite limited hepatitis and HIV screening in MMT programs nationally, this study shows that testing can be incorporated into routine procedures. MMT programs are positioned to play an integral role in the identification of patients with chronic infections, but additional guidance and resources are required to maximize their impact.
Source: Journal of Addiction Medicine - Category: Addiction Tags: Original Research Source Type: research

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Abstract The US is in the midst of a major epidemic of opioid addiction and related co-morbidities. Persons with opioid use disorder (OUD) are at significant risk for transmission of several blood-borne pathogens including the human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). Commonly abused opioids and their receptors promote viral replication and virus-mediated pathology. However, most studies demonstrating an adverse effect of drugs of abuse have been conducted in vitro, the specific effects of synthetic opioids on viral replication have been poorly characterized, and the...
Source: Current HIV Research - Category: Infectious Diseases Authors: Tags: Curr HIV Res Source Type: research
Conclusion As this was only a pilot study, further data collection involving a larger, representative sample of clients should be undertaken to explore these results further. References Bennett, H. et al., 2015. Assessing the Long-Term Impact of Treating Hepatitis C Virus (HCV)-Infected People Who Inject Drugs in the UK and the Relationship between Treatment Uptake and Efficacy on Future Infections. PLoS ONE, 10(5), p.e0125846. Edeghere, O. et al., 2015. Retrospective cohort study of liver transplantation in the United Kingdom between 1994 and 2010: the impact of hepatitis C infection. Public Health, 129(5), pp.509–5...
Source: Alcohol Research UK - Category: Addiction Authors: Tags: Alcohol Insights Source Type: news
Conclusions: SVR was not significantly associated with sociodemographic or virological characteristics, treatment, social environment, alcohol/drug use, and adherence. Although adherence was slightly worse than in “usual” patients, it did not affect the SVR rate. In these difficult-to-manage patients with HCV and substance use disorder, the real-world SVR rate (90%) was similar to that in nonaddicted populations.
Source: Journal of Addiction Medicine - Category: Addiction Tags: Original Research Source Type: research
We present the case of an 80-year-old woman, single with no children, who lived alone, and, up until presentation, was able to perform activities of daily living self-sufficiently. She reported to have the support of friends and neighbors, and she lived in the small community of São Miguel Island, Azores, Portugal. She had completed two years of college before dropping out during her third year, and her last job was as an elder care-worker. She had no personal or family psychiatric antecedents and no history of alcohol or illicit drug addictions. The patient was diagnosed with DM2 two years previously and was treate...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Case Report Current Issue acute confusional state delirium diabetes hyperglycemia psychosis Source Type: research
The latest inquiry must discover how thousands of haemophiliacs contracted HIV or hepatitis C from blood products, and why it was covered up for so longIn two weeks ’ time Sir Brian Langstaff will take up his post as chair of thepublic inquiry into contaminated blood and contaminated blood products. Today, World Haemophilia Day, is the perfect occasion to remind Langstaff what the thousands of haemophiliac victims need from this inquiry if they are to get justice.In the 1970s and 1980s more than 4,600 haemophiliacs contracted HIV or hepatitis C after being infected by contaminated blood-clotting products. Much of the...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Health Society Hepatitis B Hepatitis C Aids and HIV NHS Health policy Politics UK news Science Medical research Source Type: news
BURLINGTON (CBS) – Doctors at Lahey Hospital told Matt Higgins a new liver was his only option for survival as chronic liver disease ravaged the Seabrook, New Hampshire man’s body. “My energy levels, I was down to nothing. I could barely walk a 100 yards without having to stop. I was jaundiced, completely yellow,” Higgins told WBZ-TV. When the call came that a liver transplant was available from a 24-year-old donor who had died from an opioid overdose, Higgins said, he did not hesitate. He immediately accepted it. “Being as sick as I was, of course I said yes. I’ll take anything that&rsq...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health Local News Syndicated Local Confronting The Crisis Louisa Moller opioid crisis Organ Donation Source Type: news
Conclusion This study showed it was possible to engineer and inject instructions that transform myofibroblasts into liver cells in mice with liver disease, which is quite a feat. Not all delivery mechanisms, called vectors, worked, but in those that did, the new liver cells looked normal, replaced some of the dying cells, and led to less damage due to collagen build up. Despite the alcoholism-related headline, the mice did not have alcohol-induced liver damage – although this is a major cause of liver damage in people. This study serves to prove this approach is feasible, and was successful in doing this. Researcher...
Source: NHS News Feed - Category: Consumer Health News Tags: Genetics/stem cells Lifestyle/exercise Medical practice Source Type: news
News Roundup: President Obama Announces Actions to Address the Prescription Opioid Abuse and Heroin Epidemic • HHS Issues Guidance on Federal Funding for Syringe Services Programs • Other Recent Legislation, Guidelines, and Measures to Address Drug Addiction • CDC: 75% Increase in Reported Hepatitis C Deaths Between 2003 and 2013 • National Academies: Eliminating Hepatitis B and C Is Feasible, But Will Require Substantial Resources and Resolve • Focus on HIV Among Transgender People • HIV Treatment Dramatically Decreases Opportunistic Infections in Low- and Middle-Income Nations • Limited...
Source: AIDS Action News - Category: Infectious Diseases Source Type: news
Conclusion: The promotion of these evaluations proved beneficial, although viral screening could be achieved for only approaching half of the detainees, as could alcohol consumption assessment and HBV vaccination for those concerned. Fibrosis screening revealed lesions in HCV carriers yet also in heavy drinkers, who are typically less likely to be assessed. Consultations and HIV screening on release were found to be rarely possible.
Source: The European Journal of Public Health - Category: Journals (General) Authors: Tags: Alcohol and substance abuse Source Type: research
We present methodology for inferring important model parameters, such as those governing network structure and dynamics, from readily available data sources (e.g., epidemiological surveys). Such a model can be used to evaluate the efficacy of various programs that aim to combat drug addiction and contain blood-borne diseases among IDUs. The model is especially useful for evaluating interventions that exploit the structure of the contact network. To illustrate, we instantiate a network model with data collected by a needle and syringe program in Chicago. We model sexual and needle-sharing contacts and the consequent spread ...
Source: Mathematical Biosciences - Category: Statistics Authors: Tags: Math Biosci Source Type: research
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