Comparative results of 18F FLT and 18F FDG PET CT in lymphoma and lung cancer - a pilot study.

Conclusion: In this initial study, 18F-FLT radiotracer uptake correlated well with clinical outcome of the patients, successfully differentiating proliferative malignant lesions from other benign concomitant etiologies. Scan results demonstrated low grade to absent FLT tracer uptake in benign inflammatory/infective cells as compared to higher grade concentration in tumor cells.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Preclinical Probes for Oncology Posters Source Type: research

Related Links:

We describe a contiguous gene deletion of the ATM locus in a multi-generation family of Italian descent with a strong family history of pancreatic cancer. A deletion of one copy of the entire ATM gene was identified by routine panel testing and further characterized by chromosomal microarray analysis. An 11q22.3 microdeletion of approximately 960kb was identified that is predicted to result in loss of 10 genes including ATM. The deletion was identified in two additional family members including a presymptomatic daughter and an affected sibling. A normal disomic complement of the 11q22.3 region was detected in a third famil...
Source: Cancer Genetics - Category: Cancer & Oncology Source Type: research
ConclusionsThis case series demonstrates that the use of a high frequency jet ventilator for cardiac MRI was feasible, safe, providing good quality cardiac imaging and avoiding anesthesia personnel to be inside the hazardous environment of MRI room. Future studies are needed to confirm its safety and efficiency in pediatric patients.ResumoJustificativa e objetivosA ressonância magnética (RM) cardíaca é uma técnica utilizada na avaliação de crianças com cardiopatias congênitas. A anestesia geral garante imobilidade, especialmente em pacientes não cooperador...
Source: Brazilian Journal of Anesthesiology - Category: Anesthesiology Source Type: research
Publication date: Available online 12 October 2019Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)Author(s): Q. Xu, M. Lv, Y. Xia, Y. Zhao, W. Zhang, Y. ChenAbstractA 42-year-old woman presented with a ten-day history of dysphagia, slight chest pain and occasional vomiting. With the performance of thoracic and abdominal enhanced computed tomography (CT) and upper gastrointestinal contrast, once esophageal cancer was suspected. Significant activity mass in esophagus and mediastinal lymph nodes could be found on the imaging of 18F-FDG PET/CT, which also supported malignancy. However, T...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research
CONCLUSIONS IQGAP3 may be a potential target gene for Kaempferol in the treatment of BC, and upregulation of IQGAP3 inhibits Kaempferol-induced apoptosis in BC cells by ERK1/2 signaling activation. Targeting IQGAP3 may contribute to the study of natural phytochemicals as anti-tumor drugs in BC. PMID: 31605603 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
CONCLUSIONS PVT1 exerts an oncogenic role through activating Wnt/ß-catenin signaling in pituitary adenoma cells. The present results may provide a potential therapeutic target or approach for treating pituitary adenomas. PMID: 31604907 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
CONCLUSIONS lncRNA TSLNC8 remarkably inhibited the proliferation and migration and accelerated apoptosis of lung cancer cells by targeting the IL-6/STAT3/HIF-1alpha signaling pathway. TSLNC8 may be a potential therapeutic target for the diagnosis and treatment of NSCLC. PMID: 31601776 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Publication date: Available online 12 October 2019Source: Materials Today: ProceedingsAuthor(s): A. Saikiran, M. Vivekanand, M. Prahalad, S. Yuvan, N. RameshbabuAbstractMicrowave synthesis of nanocrystalline Zn/Mg substituted and Zn/Mg-F co-substituted hydroxyapatites is reported in this study. Substitution of Zn/Mg is expected to increase the bioactivity, whereas the fluorine substitution is aimed for the attainment of chemical and thermal stability of the hydroxyapatite. The thermal stability of the nanopowders was studied by annealing the samples at 900 °C for 2 h. The phase composition and crystallite size of t...
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
Publication date: Available online 12 October 2019Source: Materials Today CommunicationsAuthor(s): John Michael Tesha, Derrick S. Dlamini, Zhenyu Cui, Jianxin LiAbstractPolysulfone (PSF) and Styrene Maleic Anhydride (SMA) were blended by thermally induced phase separation method in the preparation of membranes for water treatment. Dipropylene Glycol Dibenzoate (DPGDB) was used as a diluent which was extracted using ethanol. The increase in SMA concentration was positively confirmed by monitoring the intensity of the peak at 1779 cm−1 characteristic to CO in the Attenuated Total Reflectance Fourier Transform In...
Source: Materials Today Communications - Category: Materials Science Source Type: research
Publication date: Available online 12 October 2019Source: Materials Today CommunicationsAuthor(s): Joby Jacob, Gregary Peter, Sabu Thomas, Józef T. Haponiuk, Sreeraj GopiAbstractBionanocomposites prepared from green sources are a promising research area and cellulose nanofibers obtained from agro-waste of ginger rhizomes and their different composites with starch, chitosan (CS) and polyvinyl alcohol (PVA) have exhibited enormous mechanical as well as antimicrobial properties. This paper reports the synthesis of magnetic ginger nanofiber (M-GNF) reinforced composite films with CS, PVA and potato starch (PS) by Fe3O4 ...
Source: Materials Today Communications - Category: Materials Science Source Type: research
Conclusions This review describes how leukocyte-heparanase can be a double-edged sword in tumor progression; it can enhance tumor immune surveillance and tumor cell clearance, but also promote tumor survival and growth. We also discuss the potential of using heparanase in leukocyte therapies against tumors, and the effects of heparanase inhibitors on tumor progression and immunity. We are just beginning to understand the influence of heparanase on a pro/anti-tumor immune response, and there are still many questions to answer. How do the pro/anti-tumorigenic effects of heparanase differ across different cancer types? Does...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
More News: Brain | Brain Cancers | Cancer | Cancer & Oncology | Chemotherapy | CT Scan | Gastric (Stomach) Cancer | Lung Cancer | Lymphoma | Neurology | Non-Small Cell Lung Cancer | Nuclear Medicine | PET Scan | Study