Evaluation of [F-18]FEONM as a PET Probe for Imaging of Tau Protein Expression in Human Glioma Bearing Mouse Models

Conclusion: Lower Tau protein expression cells (U87MG) showed a greater sensitivity to paclitaxel treatment than that of higher Tau protein expression ones (GBM8401). Our study demonstrated that [F-18]FEONM might be a promising PET probe for imaging of Tau protein expression in human gliomas. Research Support: This work was supported by grants from the Ministry of Science and Technology of Taiwan (MOST 105-2314-B-010-033-MY3 and MOST 104-2314-B-010-039-MY3).

Source: Journal of Nuclear Medicine - May 24, 2017 Category: Nuclear Medicine Authors: Li, J.-J., Chang, W.-Y., Chen, C.-C., Li, G.-Y., Lo, Y.-H., Chang, C.-W., Chen, J.-T., Chang, C.-H., Lin, W.-J., Liu, R.-S., Hwang, J.-J., Chen, C.-L., Wang, H.-E. Tags: Preclinical Probes for Oncology Posters Source Type: research