3-D PYP Score for 3-hour uptake 99mTc Pyrophosphate SPECT-CT for Transthyretin Amyloid Cardiomyopathy

Conclusion: SPECT-CT based 3-D PYP score showed an excellent sensitivity and specificity and a better diagnostic performance than the planar scintigraphy based HCL ratio for detecting ATTR-CM. Imaging at 3 hours after injection and using SPECT-CT imaging, may result in higher sensitivity for ATTR-CM by allowing background blood pool activity to resolve and avoiding overlying bony structures respectively. Research Support: None

Source: Journal of Nuclear Medicine - May 24, 2017 Category: Nuclear Medicine Authors: Garg, I., Hoffman, A., Grogan, M., Askew, J., Dispenzieri, A., Zeldenrust, S., Broski, S., Packard, A., Johnson, G. Tags: Cardiovascular Young Investigator Award Symposium Source Type: research