Drug information update. Unconventional treatment strategies for schizophrenia: polypharmacy and heroic dosing [Special articles]

The majority of patients respond to antipsychotic monotherapy at standard doses, but a subset of patients will require more heroic measures that include antipsychotic polypharmacy and high-dose monotherapy. Indeed, research has shown that roughly 30% of patients with psychosis are prescribed multiple antipsychotic medications. We discuss the potential benefits and challenges of these approaches and provide a rationale for why and when they should be utilised.

Source: Psychiatric Bulletin - June 1, 2017 Category: Psychiatry Authors: Moore, B. A., Morrissette, D. A., Meyer, J. M., Stahl, S. M. Tags: Special articles Source Type: research