Is It A Poison Ivy Rash? How To Tell — And How To Treat It

By Jessica Migala You’ve probably feared a run-in with poison ivy since you were a kid. Even brushing up against the pointy leaves is risky, says Temitayo A. Ogunleye, MD, assistant professor of dermatology at the Perelman School of Medicine at the University of Pennsylvania. The climbing plant contains an irritating resin, called urushiol, that can transfer to your skin via touch, she explains. You might also be exposed to the oily liquid by a pet who picks up the resin on his fur and then passes it along to you. You can even inhale urushiol if, say, you mow over a large patch of poison ivy in your yard, Dr. Ogunleye adds. That can cause a severe allergic reaction. But if only your skin has come into contact with the oil, you’ll likely develop an itchy, red, blistering rash within 72 hours. Of course, rashes can be triggered by all sorts of things — including laundry detergent and hair products — but poison ivy rashes tend to be geometric in nature, says Dr. Ogunleye. “Look for a blistering rash in a linear or zigzag pattern,” she says. How to treat a poison ivy rash Unfortunately, the rash can last up to three weeks, says Dr. Ogunleye. So part of poison ivy treatment is playing the waiting game until the rash goes away. To ease the itch, apply an over-the-counter hydrocortisone cream. You can also take an OTC oral antihistamine, such as Allegra or Benadryl. If the rash isn’t starting to get better after a couple ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Ciguatera fish poisoning (CFP) is caused by the consumption of fish contaminated with ciguatoxins (CTXs). The most distressing symptoms are cutaneous sensory disturbances, including cold dysesthesia and itch. CTXs are neurotoxins known to activate voltage-gated sodium channels (Nav) but no specific treatment exists. Peptidergic neurons have been critically involved in CFP sensory disturbances. Protease-activated receptor-2 (PAR2) is an itch- and pain- related G protein-coupled receptor whose activation leads to a calcium-dependent neuropeptide release.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
-- A poison ivy rash is caused by coming in contact with the oil found in the plant. The rash is very itchy and can be accompanied by redness, swelling, hives and crusting skin, says the American Academy of Dermatology. To manage a poison ivy rash,...
Source: - Daily MedNews - Category: General Medicine Source Type: news
Ciguatera Fish Poisoning (CFP) is a widespread tropical intoxication consecutive to ciguatoxin (CTX) ingestion, which is characterized by persistent neuro-cutaneous disturbances, including an intense pruritus (itch). Currently, there is no specific treatment. The primary target of CTXs is the voltage dependent sodium channel (Nav), which is largely expressed in sensory nerves and, to a lesser extent, in keratinocytes. By activating Nav, CTXs induce neuronal hyper-excitability but the downstream molecular mechanisms leading to sensory disorders are poorly understood.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Innate Immunity and Inflammation Source Type: research
Poison ivy and other poisonous plants are a hazard year-round. Here are tips for preventing and treating the itchy rash and blisters.
Source: FDA Center for Drug Evaluation and Research - What's New - Category: Drugs & Pharmacology Authors: Source Type: news
We examined the expression of TRPV1 in peripheral tissue and DRG neurons of CPIP model rats and we studied whether CPIP model could induce peripheral sensitization of TRPV1 channel and enhance DRG neuron excitability. Then we examined the therapeutic effects of locally applied TRPV1 specific antagonist AMG9810 on pain responses of CPIP model rats. Lastly, we explored the effects of AMG9810 on DRG neuron hyperexcitability and spinal glial activation induced by CPIP. Our results demonstrate that TRPV1 plays an important role in mediating the behavioral hypersensitivity of CPIP model rats via promoting peripheral nociceptor a...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
In this study we used HPLC and LC/MS analysis, combined with a BATMAN-TCM platform, for detailed HPLC fingerprint analysis and network pharmacology of QP, and investigated the anti-inflammatory and antipruritic activities of QP on ACD induced by squaric acid dibutylester (SADBE) in mice. The BATMAN-TCM analysis provided information of effector molecules of the main ingredients of QP, and possible chronic dermatitis-associated molecules and cell signaling pathways by QP. In ACD mice, QP treatment suppressed the scratching behavior induced by SADBE in a dose-dependent manner and inhibited the production of Th1/2 cytokines in...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
-- If you've been near or touched poison ivy, you may develop an itchy, blistering rash within 12 to 72 hours. Most everyone reacts to an oil in the poison ivy plant called urushiol. The rash typically goes away on its own in a few weeks, but some...
Source: - Daily MedNews - Category: General Medicine Source Type: news
If you're spending time outdoors in the brush, you're also at higher risk of brushing up against a poisonous plant. Exposure to plants like poison ivy can cause an itchy rash that lasts for weeks.? So how do you treat it? Jason Howland has more in this Mayo Clinic Minute. Watch: The Mayo Clinic [...]
Source: News from Mayo Clinic - Category: Databases & Libraries Source Type: news
If you have mesothelioma and you’ve already received standard-of-care therapies, you may be considering an immunotherapy clinical trial. If you’re considering this option, a free immunotherapy teleconference is a great place to learn more. CancerCare recently hosted two one-hour education workshops featuring panels of immunotherapy experts. Part I of the teleconference presented an overview of immunotherapy. Part II of the teleconference, which is available online for free, focused exclusively on immunotherapy side effects. Understanding these issues and the role each patient plays in managing their own side ef...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
Cooling is an effective temporary remedy for itch, bringing welcome relief to itchy insect bites, nettle stings, poison ivy, atopic dermatitis, and psoriasis. Menthol, causing a cooling sensation, has similar itch-relieving effects. Palkar et  al. demonstrate that TRPM8, a menthol- and cold-activated ion channel, is essential for cooling to relieve itch, suggesting that pharmacologic TRPM8 activation should be explored further as an antipruritic strategy.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Commentary Source Type: research
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