Cancer therapy shows promise for psoriasis treatment

(Medical College of Georgia at Augusta University) HDAC inhibitors, already widely used to treat cancer, may be an effective therapy for psoriasis as well, scientists report.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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Authors: Gehoff M, Augustin M Abstract There are diseases that are noticeable for the respective patients, but not visible for all others. And there are skin diseases which, due to their clearly visible location on the skin surface, are often easily recognisable to others. Nevertheless, in recent years dermatology has changed from a traditional optical subject, characterized by clinical observation, to a causal-oriented subject. At ever shorter intervals, new therapeutic options are emerging which present dermatology with a multitude of challenges. This raises questions not only about benefits and ef...
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
Publication date: Available online 9 August 2018Source: CytotherapyAuthor(s): HANREN DAI, YONG ZHOU, CHUAN TONG, YELEI GUO, FENGXIA SHI, YAO WANG, PINGPING SHENAbstractPsoriasis is a chronic inflammatory skin disorder mediated by the cells and molecules of both the innate and adaptive immune systems. Autologous cytokine-induced killer (CIK) cell infusion is considered an effective and safe cancer treatment and is licensed for this use in China. Accumulated evidence indicating that CD3+CD56+ cells are significantly decreased in psoriatic patients prompted us to investigate if the restoration of CD3+CD56+ cells may be benefi...
Source: Cytotherapy - Category: Cytology Source Type: research
CONCLUSION: The treatment of skin diseases based on topical delivery of siRNA, which act by inhibiting the expression of target transcripts, offers many potential therapeutic advantages for suppressing genes into the skin. PMID: 30084329 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
We may now have an explanation for the people who experience brain fog with probiotic use. We already know that intolerance to prebiotic fibers within the first 60 minutes of ingestion have small intestinal bacterial overgrowth, SIBO. If you experience excessive gas, bloating, abdominal discomfort, or diarrhea within the first hour of consuming, say, inulin, a raw white potato, or legumes, it is virtually certain that you have SIBO that must be addressed if you desire full recovery of health. Recall that uncorrected SIBO can account for fibromyalgia, IBS, restless leg syndrome, psoriasis, and marked long-term potential for...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates Source Type: blogs
Introduction: Psoriasis patients report quality of life (QoL) comparable to certain types of cancer. Digital tools may improve overall care and life quality. We developed a novel interactive digital telemedicine follow-up mobile application that provides patients with assessments of their psoriasis severity based on self-taken pictures. We assessed patients ’ perception of the app and its impact on patients’ QoL.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Background: Psoriasis is a chronic inflammatory disease with a significant negative effect on patient quality of life (QoL). The impact of psoriasis on QoL is similar to that of other chronic diseases, such as diabetes and cancer. A structured online survey was conducted to explore factors that influence QoL in patients with psoriasis.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
A screening colonoscopy identified an unexpected diagnosis in a 64-year-old male patient. He is an asymptomatic landscaper who presented for a first-time screening colonoscopy based upon age. His only active medical issue is psoriasis for which he takes apremilast. At the time of colonoscopy, he denies any bright red blood per rectum, melena, changes in stooling habits, abdominal pain, nausea, vomiting, changes in appetite, weight loss, or night sweats. He does not report any family history of colon cancer.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Diagnostic Dilemma Source Type: research
British Journal of Dermatology, EarlyView.
Source: British Journal of Dermatology - Category: Dermatology Authors: Source Type: research
säter H Abstract With increasing numbers of children being diagnosed with neurodevelopmental disorders (NDDs) attention has been drawn to these children's physical health. We aimed to identify the prevalence of defined physical problems (epilepsy, migraine, asthma, cancer, diabetes, psoriasis, lactose intolerance, celiac disease, diarrhea, constipation, daytime enuresis, encopresis) in a nationwide population of 9- and 12-year-old twins subdivided into those with and without indications of NDDs. Parents of 28,058 twins participated in a well-validated telephone interview regarding their children's mental heal...
Source: Journal of Autism and Developmental Disorders - Category: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research
(University of Pennsylvania School of Medicine) Cancer patients receiving anti-PD-1 therapies who develop lesions, eczema, psoriasis, or other forms of auto-immune diseases affecting the skin may experience those adverse reactions on a delay -- sometimes even after treatment has concluded.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
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