Postnatal hyperoxia or DEHP exposure leads to growth restriction and delayed lung development in newborn rats

Di-(2-ethylhexyl) phthalate (DEHP) is commonly used as a plasticizer in many medical devices. We previously showed that maternal DEHP exposure led to restricted growth and delayed lung maturation in newborn rats. As oxygen toxicity continues to be a major risk factor for bronchopulmonary dysplasia, the aim of this study was to examine the effect of hyperoxia, DEHP or DEHP combined with hyperoxia on the growth and lung maturation of newborn rats.

Source: Pediatrics and Neonatology - May 30, 2017 Category: Perinatology & Neonatology Authors: Zhong-Jie Liang, Qiu-Ping Wu, Bei-Tao Chen, Zhen-lang Lin, Jing Lin, Shang-Qin Chen Tags: Original Article Source Type: research