In  vitro effects of Zinc in soluble and homeopathic formulations on macrophages and astrocytes.

In vitro effects of Zinc in soluble and homeopathic formulations on macrophages and astrocytes. Homeopathy. 2017 May;106(2):103-113 Authors: Bonafini C, Marzotto M, Bellavite P Abstract Zinc is an important metal in body homeostasis. Zinc in soluble form (Zn(2+)) and homeopathic Zincum metallicum were tested in macrophages and astrocytes in order to investigate its potential toxic or therapeutic effects. We evaluated cell viability (WST assay), cytokine production such as tumour necrosis factor alpha (TNF-α) and interleukin 10 (IL-10) by enzyme-linked immunosorbent assay (ELISA) and nitric oxide release by Griess reaction. The effect of zinc-depletion and high zinc pre-treatments on the cell adaptation capability was also investigated. In THP-1 macrophage cell line and in human primary macrophages, Zn(2+) at sub-toxic doses (30 μM) caused stimulation of TNF-α and IL-10 with different dynamics reaching the maximum peak at the zinc concentration 100 μM, before the cell death. Highest doses (300 μM) impaired dramatically cell vitality. Similar effects on cell viability were obtained also in C6 astrocytes, where Zn(2+) slightly increased the nitric oxide release only in cells activated by one of the pro-inflammatory stimuli used in our cellular model (interferon gamma plus TNF-α). Zinc depletion markedly reduced IL-10 production and cell viability. Zincum metallicum did not cause toxicity in any cell type and sh...
Source: Homeopathy - Category: Complementary Medicine Authors: Tags: Homeopathy Source Type: research

Related Links:

Contamination at a North Carolina-based homeopathic manufacturer has led to further recalls
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Eight and Company LLC, d/b/a Sprayology is voluntarily recalling all lots within expiry from 10/18-7/22 of its aqueous-based homeopathic product line for human use. All products manufactured by the contract manufacturer, King Bio, have been recalled due to possible microbial contamination.
Source: Food and Drug Administration - Category: Food Science Source Type: news
ConclusionArthritis, neuritis and fungal diseases were the most common morbidities, for which patients sought care in Siddha hospitals. These morbidities can be considered for preparing standard treatment guidelines under the national programme.
Source: Journal of Ayurveda and Integrative Medicine - Category: Complementary Medicine Source Type: research
Peer-reviewed homeopathy study sparks uproar in Italy, Published online: 09 October 2018; doi:10.1038/d41586-018-06967-0Advocates of homeopathy say that the rat study is evidence of the practice’s efficacy, but some scientists have cast doubt on the paper.
Source: Nature AOP - Category: Research Authors: Source Type: research
Daily briefing: How to beat the academic job odds, Published online: 09 October 2018; doi:10.1038/d41586-018-07002-yHow to score a permanent research position, a hiccup on the Hubble, and a controversial peer-reviewed homeopathy study.
Source: Nature AOP - Category: Research Authors: Source Type: research
Publication date: Available online 6 October 2018Source: Journal of Herbal MedicineAuthor(s): Harish Chandra Chaudhury, Akhil Kumar Panda, Sarat Kumar Behera, Manjushree Mohanty, Bharat Bhusan SubudhiAbstractPhytolacca Americana Lor pokeweed has medicinal application against inflammation, arthritis, and viral fever infections in traditional medicines. Its mother tincture in the homeopathic system of medicine is used for many of these disease conditions. This is the first case study reporting the beneficial effects of Phytolacca-mother tincture against Japanese Encephalitis Virus (JEV) infection in an intensive care unit (I...
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research
Abstract BACKGROUND:  Practice-based registration could identify 'general' and 'homeopathic' prognostic factors for therapeutic success in patients who seek complementary and alternative medicine (CAM)/homeopathic treatment. Identification of 'best homeopathic cases' within a database could inform clinical research and improve homeopathic practice. OBJECTIVE: To investigate the feasibility of registration in daily CAM/homeopathic practice, evaluate patient-reported outcome measures and tools for identifying 'best homeopathic cases' and to make recommendations for an electronic database. METHODS: &em...
Source: Homeopathy - Category: Complementary Medicine Authors: Tags: Homeopathy Source Type: research
CONCLUSION:  The non-specific, pro-inflammatory effects might be attributed to organic residuals detached from the vials' plastic walls during manipulation. Instead, specific silica-independent effects of the homeopathic medicine can be attributed to the decrease of interleukin-6 after treatment with the 200th centesimal dilution of arsenic. PMID: 30290377 [PubMed - as supplied by publisher]
Source: Homeopathy - Category: Complementary Medicine Authors: Tags: Homeopathy Source Type: research
(Natural News) The basic fundamental concept of how a vaccine works is homeopathy based, thus treating disease by minute doses of natural substances that, in a healthy person, produce the systems of disease. There’s one massive problem with inoculations in this regard. Today’s immunizations not only contain some natural ingredients, but they also contain the...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Source: Acta Diabetologica - Category: Endocrinology Source Type: research
More News: Complementary Medicine | Homeopathy | Statistics | Toxicology | Zinc