Pathologic Impact of Insulin Resistance and Sensitivity on the Severity of Liver Histopathology in Pediatric Non-Alcoholic Steatohepatitis.

CONCLUSION: Patients with high IR had more severe lobular inflammation and hepatic fibrosis. Analyses of biochemical and endocrine parameters can be applied to determine the severity of the hepatic pathologic status in patients with NASH, especially in children who cannot undergo a liver biopsy. PMID: 28540988 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/28540988?dopt=Abstract

Source: Yonsei Medical Journal - May 27, 2017 Category: Universities & Medical Training Authors: Park BH, Yoon JM, Kim JH, Moon JH, Lee YH, Jang SM, Kim YJ Tags: Yonsei Med J Source Type: research