Could a Century-Old Drug Help Ease Autism Symptoms?

FRIDAY, May 26, 2017 -- A drug first used in the early 1900s to treat sleeping sickness has shown promise in an early trial as a potential treatment for autism. The study involved just 10 boys, aged 5 to 14, with autism. This was the first human...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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Conclusions: Results indicate that maternal thyroid conditions are associated with increased ASD risk in progeny, but suggestively not due to direct effects of thyroid hormones. Instead, factors that influence maternal thyroid function could have etiologic roles in ASD through pathways independent of maternal gestational thyroid hormones and thus be unaffected by medication treatment. Factors known to disrupt thyroid function should be examined for possible involvement in ASD etiology.
Source: Epidemiology - Category: Epidemiology Tags: Women’s Health Source Type: research
Individuals with autism spectrum disorder (ASD) are often behaviorally hyper-reactive to light touch, but it is unclear to what degree this arises from a fundamental sensory difference vs. higher order systems for attention or emotion processing. Thus far, experimental findings for light touch detection are mixed, and few previous studies have independently considered sensitivity (the ability to discriminate signal from noise) and decision criterion (the overall response bias or tendency to answer “yes” or “no” in a detection task). We tested a large sample of children, adolescents, and adults with ...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
In addition to all the worry and uncertainty in the midst of the COVID-19 pandemic, Vanessa Coens is concerned about her two boys with autism regressing during this period of self-isolation.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/Windsor Source Type: news
Autistic individuals experience elevated risk for suicide ideation, attempts, and deaths. Little is known about how clinicians assess risk or intervene with suicidal autistic individuals. We surveyed 121 clinicians about use of suicide prevention practices...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
hello all!! I am just looking for any advice/guidance I can get. But my plan didn’t work out this year so I am planning on re-applying in 2021. My undergraduate GPA is 3.5 and science is 3.2. And I got 497 on MCAT. I am definitely going to retake the MCAT. I am trying to figure out how to best stay productive and use the next two years to my advantage to set my application apart. I currently work at a great company as a registered behavioral technician with children with autism. I am... GAP YEAR advice please!!!
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Re-Applicants [ MD / DO ] Source Type: forums
r P Abstract Suramin is a hundred years old and still being used to treat the first stage of acute human sleeping sickness, caused by Trypanosoma brucei rhodesiense Suramin is a multifunctional molecule with a wide array of potential applications, from parasitic and viral diseases to cancer, snakebite and autism. Suramin is also an enigmatic molecule: What are its targets? And how does it get into cells in the first place? Here we provide an overview on the many different candidate targets of suramin, discuss modes of action, and routes of cellular uptake. We reason that once the polypharmacology of suramin is und...
Source: Antimicrobial Agents and Chemotherapy - Category: Microbiology Authors: Tags: Antimicrob Agents Chemother Source Type: research
Small study produced positive results with the sleeping sickness medication suramin, but more research needed
Source: WebMD Health - Category: Consumer Health News Source Type: news
(University of California - San Diego) In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, was safely administered to children with autism spectrum disorder (ASD), who subsequently displayed measurable, but transient, improvement in core symptoms of autism.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Congratulations to Disruptive Women in Health Care Dr. Concetta Tomaino who continues to show us the power of music to heal. The following post by Deborah Harkins first appeared in Women’s Voices for Change on July 11, 2016. Concetta Tomaino with her late colleague Dr. Oliver Sacks, to whom Dustin Hoffman presented the Music Has Power award in 2006. Music! We know it can stimulate, excite, soothe, transport . . . . indeed, it sometimes sparks emotion so pleasurable that it actually sends chills down the spine. (Like sex, cocaine other abused drugs, and food, music triggers the area of the brain that release...
Source: Disruptive Women in Health Care - Category: Consumer Health News Authors: Tags: Uncategorized Source Type: blogs
Researchers previously reported that a drug used for almost a century to treat trypanosomiasis, or sleeping sickness, reversed environmental autism-like symptoms in mice. Now, a new study suggests that a genetic form of autism-like symptoms in mice are also corrected with the drug, even when treatment was started in young adult mice.
Source: ScienceDaily Headlines - Category: Science Source Type: news
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