Acetylcholinesterase and butyrylcholinesterase in cardiosurgical patients with postoperative delirium

ConclusionsPostoperative measurement of AChE and BChE did not discern between patients with and without POD. The effect of the cardiac surgical procedure on AChE and BChE remains unclear. Further studies with patients in cardiac surgery are needed to evaluate a possible combination of delirium and the cholinergic transmitter system. There might be possible interactions with AChE/BChE and blood products and the use of cardiopulmonary bypass, which should be investigated more intensively.Trial registrationGerman Clinical Trials Register,DRKS00006217
Source: Journal of Intensive Care - Category: Intensive Care Source Type: research