Log in to search using one of your social media accounts:

 

New Ebola outbreak rings alarm bells early

Source: ScienceNOW - Category: Science Authors: Tags: Epidemiology, Immunology, Pharmacology, Toxicology, Virology In Depth Source Type: news

Related Links:

by Peter J. Hotez Within the last five years, the State of Texas has experienced either transmission or outbreaks of Ebola, chikungunya, West Nile, and Zika virus infections. Autochthonous transmission of neglected parasitic and bacterial diseases has also become increasingly reported. The rise of such emerging and neglected tropical diseases (NTDs) has not occurred by accident but instead reflects rapidly evolving changes and shifts in a “new” Texas beset by modern and globalizing forces that include rapid expansions in population together with urbanization and human migrations, altered transportation pa tter...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
M. Winters et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
We describe implementation of the Xpert Ebola Assay, a rapid molecular diagnostic test run on the GeneXpert platform, at a mobile laboratory in Liberia and the subsequent impact on EVD outbreak response, case mana gement and laboratory system strengthening. During the period of operation, site coordination, management and operational capacity was supported through a successful collaboration between Ministry of Health (MoH), World Health Organization (WHO) and international partners. A team of Liberian laborat ory technicians were trained to conduct EVD diagnostics and the laboratory had capacity to test 64–100 blood ...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
This article explores the potential for a syndromic system/Shewhart control chart based on the online interaction with a national travel health Web site in comparison with searches on the Google UK search engine. The study showed an amplification of perceived risk among users of a national travel health Web site months before the World Health Organization declared the outbreak a Public Health Emergency of International Concern and the initial surge in public interest on Google UK in August 2014.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
Publication date: Available online 2 January 2018 Source:Antiviral Research Author(s): Baptiste Martin, Olivier Reynard, Viktor Volchkov, Etienne Decroly There are no approved medications for the treatment of Marburg or Ebola virus infection. In two previous articles (Martin et al., 2016, Martin et al., 2017), we reviewed surface glycoprotein and replication proteins structure/function relationship to decipher the molecular mechanisms of filovirus life cycle and identify antiviral strategies. In the present article, we recapitulate knowledge about the viral proteins involved in filovirus assembly and budding. First we des...
Source: Antiviral Therapy - Category: Virology Source Type: research
Abstract There are no approved medications for the treatment of Marburg or Ebola virus infection. In two previous articles (Martin et al., 2016, Martin et al., 2017), we reviewed surface glycoprotein and replication proteins structure/function relationship to decipher the molecular mechanisms of filovirus life cycle and identify antiviral strategies. In the present article, we recapitulate knowledge about the viral proteins involved in filovirus assembly and budding. First we describe the structural data available for viral proteins associated with virus assembly and virion egress and then, we integrate the struct...
Source: Antiviral Research - Category: Virology Authors: Tags: Antiviral Res Source Type: research
Conclusions: Coordination between the public health sector and the curative sector needs improvement to reduce delay in patient management in emerging infectious diseases. Standardization of preparedness and response practices, through guidelines for institutional preparedness and blueprints for regional and national coordination, is necessary, as preparedness for emerging infectious diseases needs a multidisciplinary approach overarching both the public health sector and the curative sector. In the Netherlands a national platform for preparedness is established, in which both the curative sector and public health sector...
Source: Journal of Public Health Management and Practice - Category: Health Management Tags: Research Reports: Research Full Report Source Type: research
Publication date: Available online 28 December 2017 Source:Antiviral Research Author(s): Sandra L. Bixler, Thomas M. Bocan, Jay Wells, Kelly Wetzel, Sean Van Tongeren, Nicole Lackemeyer, Ginger Donnelly, Lisa Cazares, Veronica Soloveva, Lisa Welch, Carol Epstein, Li-Fang Liang, Dennis Giesing, Robert Lenk, Sina Bavari, Travis K. Warren During the 2013–2016 Ebola virus (EBOV) outbreak in West Africa, our team at USAMRIID evaluated the antiviral activity of a number of compounds, including favipiravir (T-705), in vitro and in mouse and nonhuman primate (NHP) models of Ebola virus disease. In this short communication, ...
Source: Antiviral Therapy - Category: Virology Source Type: research
Abstract During the 2013-2016 Ebola virus (EBOV) outbreak in West Africa, our team at USAMRIID evaluated the antiviral activity of a number of compounds, including favipiravir (T-705), in vitro and in mouse and nonhuman primate (NHP) models of Ebola virus disease. In this short communication, we present our findings for favipiravir in cell culture and in mice, while an accompanying paper presents the results of NHP studies. We confirmed previous reports that favipiravir has anti-EBOV activity in mice. Additionally, we found that the active form of favipiravir is generated in mice in tissues relevant for the pathog...
Source: Antiviral Research - Category: Virology Authors: Tags: Antiviral Res Source Type: research
TUESDAY, Dec. 26, 2017 -- The immune systems of people who survived the first Ebola outbreak 40 years ago appear to be protecting them against future infection with the deadly virus, a new study finds. The discovery could help in efforts to develop...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
More News: Allergy & Immunology | Drugs & Pharmacology | Ebola | Epidemiology | Outbreaks | Toxicology | Virology