Feasibility of the Von Willebrand disease PREVENT trial

Despite treatment, women with von Willebrand disease (VWD) have lower von Willebrand factor (VWF) levels and greater blood loss at delivery than controls. Current weight-based dosing does not account for the ~1.5-fold increase in blood volume in pregnancy.

Source: Thrombosis Research - May 25, 2017 Category: Hematology Authors: Margaret V. Ragni, Nicoletta Machin, Andra H. James, Craig D. Seaman, Lynn M. Malec, Craig M. Kessler, Barbara A. Konkle, Peter A. Kouides, Anne T. Neff, Claire S. Philipp, Maria M. Brooks Tags: Full Length Article Source Type: research