The 7 Injuries Doctors See Most On Summer Weekends

Warm weather and longer days will bring many Americans outdoors for cookouts, pool parties and more. But long weekends ― we’re looking at you, Memorial Day ― also lead to more trips to urgent care or even the emergency room, according to experts. In fact, a 2015 study from researchers at Brown University found that heat-related illness alone can ratchet emergency department visits in the summertime.  The risk for issues like drowning and sports injuries go up in the hotter seasons, according to Dr. Christopher M. McStay, chief of clinical operations and associate professor at the University of Colorado School of Medicine. And they’re usually all preventable. We asked doctors to explain the most common reasons why patients end up in their offices during summer months ― and what can be done to prevent you or a loved one from being among them. 1. Heat-related illness. During summer months, people often show up at the doctor with a heat-related condition, from mild dehydration to severe heatstroke, says Dawne Kort, an emergency medicine doctor and attending physician at CityMD Urgent Care Walk-In Medical Clinic.  Fewer than 1,000 Americans die each year due to heat-related illness, according to a 2014 study by the Centers for Disease Control and Prevention. But plenty more experience the more mild symptoms of too much sun exposure, which include nausea, dizziness, headaches and confusion.  “Be mindful of the temperature, stay ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Erratum: P130cas is required for TGF-β1-mediated epithelial-mesenchymal transition in lung cancer. Oncol Lett. 2020 Apr;19(4):3358 Authors: Deng B, Tan QY, Wang RW, Jiang YG, Zhou JH, Huang W Abstract [This corrects the article DOI: 10.3892/ol.2014.2123.]. PMID: 32218871 [PubMed - as supplied by publisher]
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Authors: Wang S, Meng C, Jiang Z, Gonzalez-Rivas D, Ruan J, Xu W, Liu C, Zhang L, Gao G, Yu G, Teng H, Ju J Abstract [This corrects the article DOI: 10.3892/ol.2019.10030.]. PMID: 32218870 [PubMed - as supplied by publisher]
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Authors: Lu F, Cui D, Mu B, Zhao L, Mu P Abstract Tropomodulin-1 (TMOD1) is a key regulator of actin dynamics, which caps the pointed end of actin filaments. TMOD1 has been reported to be involved in several cellular processes, including neurite outgrowth, spine formation and cell migration. Increasing evidence demonstrates that TMOD1 is implicated in several aspects of cancer development. The present study aimed to investigate the role of TMOD1 in cervical cancer. HeLa and CaSki cell lines, derived from human cervical cancer, were used to evaluate the function of TMOD1. Cell motility was measured via a wound-heali...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Authors: Tian X, Wang N Abstract Pancreatic ductal adenocarcinoma (PDAC) remains a major cause of cancer-associated mortality, with poor patient outcome. The present study aimed to identify key candidate genes and investigate the potential molecular mechanisms associated with the progression of PDAC. The GSE46234 dataset was downloaded from the Gene Expression Omnibus database, in order to identify the upregulated differentially expressed genes (DEGs) in PDAC. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed to determine the biological functions and pathways of the upreg...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Authors: Zhang Y, Bi L, Hu Z, Cao W, Zhuang D Abstract It has been found that>90% of oral cancer patients suffer from squamous cell carcinoma (SCC). The 5-year survival rate of SCC is ~50%, despite the availability of different treatments. Sonodynamic therapy (SDT) has been developed as a novel therapy for cancer, resisting bacterial infection and inhibiting atherosclerotic plaque progression. The present study investigated the efficacy of hematoporphyrin monomethyl ether (HMME)-mediated SDT on the A-253 epidermoid cancer cell line. The cytotoxicity of HMME and the survival rate of cells following SDT were exami...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Authors: Liang H Abstract The aim of the present study was to determine the mechanism by which advanced glycation end products (AGEs) induce proliferation, invasion and epithelial-mesenchymal transition (EMT) of human colon cancer SW480 cells. SW480 cells were divided into groups as follows: i) Control; ii) cells treated with AGEs alone; and iii) cells treated with AGEs combined with LY294002. Proliferation, cell cycle progression, apoptosis, invasion and migration of SW480 cells were assessed using an MTT assay, flow cytometry, Transwell assays and a wound healing assay, respectively. The protein expression levels...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Authors: Wang J, Yang X, Han S, Zhang L Abstract Disrupted centrosome-associated family protein expression can result in the detrimental duplication of centrosomes, causing genomic instability and subsequent carcinogenesis. Limited research has demonstrated that centrosomal protein 131 (CEP131) exhibits oncogenic activity in osteosarcoma, hepatocellular carcinoma and breast cancer. The present study demonstrated that there is an association between CEP131 expression and advanced Tumor-Node-Metastasis stage (P=0.016), and positive regional lymph node metastasis (P=0.023) in 91 cases of non-small cell lung cancer. A5...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Authors: Nakata E, Sugihara S, Sugawara Y, Nakahara R, Furumatsu T, Tetsunaga T, Kunisada T, Nakanishi K, Akezaki Y, Ozaki T Abstract Malignant spinal cord compression (MSCC) is a serious complication of cancers. The present study aimed to establish a multidisciplinary treatment system for urgent magnetic resonance imaging (MRI) and referral to orthopedists in order to prevent neurological deficits caused by MSCC. In the present study, the extent to which this system achieved early diagnosis and treatment and prevented MSCC-caused neurological deficits was examined. The records from patients with neurological defic...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Authors: Zhou DN, Ye CS, Yang QQ, Deng YF Abstract Non-coding RNAs (ncRNAs) regulate numerous genes and influence the progression of various human diseases, including cancer. The role of regulatory ncRNAs implicated in nasopharyngeal carcinoma (NPC), as well as their target genes, remains unclear. The present study aimed to investigate specific long non-coding (lnc)RNAs, circular RNAs (circRNAs) and mRNAs associated with the molecular pathogenesis of NPC, and to predict the underlying target genes of specific lncRNAs and circRNAs. The expression levels of lncRNAs, circRNAs and mRNAs in NPC and chronic nasopharyngit...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
In conclusion, the present study revealed that the upregulation of RBM47 accelerated the malignant progression of NSCLC, indicating that RBM47 may be a potential biomarker for NSCLC progression and a therapeutic target for NSCLC. PMID: 32218862 [PubMed - as supplied by publisher]
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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