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Voice Outcomes in Surgical Repair of Zenker ’s Diverticulum

AbstractThe purpose of the study was to define the impact of Zenker ’s diverticula on voice and potential benefit from repair. Retrospective chart review of prospectively collected data from eleven patients with a Zenker’s diverticulum treated surgically in a tertiary care center from November 2014 through January 2016. The voice handicap index-10 (VHI-10) and e ating assessment tool-10 (EAT-10) questionnaires were collected as part of pre- and post-operative evaluation, with an average post-operative follow-up of 69 days. Surgical techniques included: trans-oral endoscopic diverticulotomy with laser assistance, or trans-cervical approach with diverticulop exy or diverticulectomy. The primary outcome was subjective voice improvement. Secondary outcome was swallowing function improvement. Statistical analysis was performed using Wilcoxon Signed-Ranks and Mann–WhitneyU tests. In patients undergoing surgical treatment of Zenker ’s diverticula, there is a statistically significant improvement (p = 0.001) in patient-reported dysphagia symptoms measured by the EAT-10. There is also a clinically relevant improvement in subjective voice quality (average pre-operative total 6.55, post-operative 2.09,p = 0.022) as measured by the VHI-10. Many patients suffering from Zenker’s diverticula experience subjective voice handicap. Most note improvement in voice quality post-operatively, which we were able to quantify using the voice handi...
Source: Dysphagia - Category: Speech-Language Pathology Source Type: research

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ConclusionsThe predictive value of demonstrable SUI in symptomatically continent women undergoing vaginal prolapse repair is limited. Urodynamics added no value. The twenty‐eight percent POSUI risk must be balanced against the increased complication risk if a prophylactic midurethral sling is considered.
Source: Neurourology and Urodynamics - Category: Urology & Nephrology Authors: Tags: ORIGINAL CLINICAL ARTICLE Source Type: research
Authors: Ochiumi Y, Suzuki Y, Oba Y Abstract A 70-year-old man, who had undergone the placement of an endovascular aneurysm repair graft for an abdominal aortic aneurysm 7 years previously, presented to our facility with the separation of a left iliac stent-graft limb from the main-body stent-graft, resulting in a type III endoleak. An attempt was made to repair the disconnected stent-graft limb with endovascular intervention. An extension stent-graft was successfully deployed using a pulled-through technique to connect the main-body stent-graft with the disconnected stent-graft limb. Endovascular intervention may ...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
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Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: General Surgery News Source Type: news
Abstract Ketamine-induced ulcerative cystitis (KIC) initially damaged the bladder mucosa and induced contracted bladder thereafter. Hyaluronan (hyaluronic acid; HA) instillation to the bladder has been used to treat KIC. The present study investigated bladder injury by urothelial defect and HA degeneration and bladder repair by urothelium proliferation and differentiation. This work was based on the hypothesis that HA treatment altered the bladder urothelial layer and the expression of hyaluronan-metabolizing enzymes and/or HA receptors in KIC. Cystometrogram study and tracing analysis of voiding behavior revealed...
Source: The American Journal of Pathology - Category: Pathology Authors: Tags: Am J Pathol Source Type: research
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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Alternative and Nutritional Supplements Depression Exercise & Fitness Habits Mental Health and Wellness Research Self-Help active lifestyle Cardio Depressive Episode Fitness Training Mood Disorder working out Source Type: blogs
One of the ways in which cells communicate and react to one another is via vesicles, small membrane-wrapped packets of proteins. Cell signaling in general is an important part of the detrimental effects of senescent cells on tissue function and health, and so changes in signal mechanisms might prove to be a useful marker of the presence of such cells. Now that therapies based on clearance of senescent cells are under active commercial development, there is considerable interest in the scientific community in better ways to identify and classify senescence in tissues. This open access paper is an example of the sort of rese...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
This report describes a patient with a left  pelvic renal transplant with distal ureteral stenosis status post pyelovesicostomy with anastomotic stenosis of the pyelovesicostomy.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Special Letter Section Source Type: research
Nonthrombotic iliac vein compression syndrome, or May –Thurner syndrome (MTS), is a vascular compression syndrome that most commonly results from extrinsic compression of the left common iliac vein by the right common iliac artery (1). Clinical findings include dilation of collateral veins to facilitate venous outflow, deep vein thrombosis (DVT), and left lower-extremity varicosities. Venous aneurysm is a phenomenon that may rarely be associated with MTS. The present report describes a patient with symptomatic MTS-related venous aneurysm that was successfully treated with endovascular repair of the venous outflow obstruction.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Special Letter Section Source Type: research
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Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Special Letter Section Source Type: research
Percutaneous suprapubic cystolitholapaxy (PSCL) is largely performed in the pediatric population for the treatment of  bladder calculi in augmented and native bladders. It is rarely performed in adults, in whom open cystolithotomy or transurethral cystoscopic techniques are generally employed. However, a transurethral approach is precluded in patients born with bladder exstrophy who have had previous Mitrofanoff procedures as children and in whom the bladder neck is closed. First described by Mitrofanoff in 1980 (1), the procedure involves creation of a urinary diversion and stoma fashioned from the appendix (2),...
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Special Letter Section Source Type: research
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