Management of the Clinically Node-Negative Axilla in Primary and Locally Recurrent Breast Cancer.

Management of the Clinically Node-Negative Axilla in Primary and Locally Recurrent Breast Cancer. Surg Oncol Clin N Am. 2014 Jul;23(3):463-471 Authors: McGinity AC, Lautner MA, Jatoi I Abstract For patients with primary breast cancer, nodal status remains a key determinant for overall prognosis. Sentinel lymph node biopsy (SLNB) has become standard care for staging patients who have clinically node-negative disease. However, a new dilemma has arisen: how to manage the clinically negative axilla in patients with ipsilateral breast tumor recurrences (IBTRs). Are outcomes in these patients improved with repeat SLNB? Although observational studies suggest SLNB is feasible in patients with IBTR and a clinically node-negative axilla, the overall impact on morality and local recurrence is not yet known as no randomized trials have addressed this issue. PMID: 24882345 [PubMed - as supplied by publisher]
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: Surg Oncol Clin N Am Source Type: research