Stepping Up Global Health Towards Resilient, Responsible and Responsive Health Systems

B20 Germany. 05/16/2017 This 59-page report details the need to improve resilience and sustainability of health systems; ensure a more sustainable, pro-innovation environment; and establish a more collaborative culture among all stakeholders. It discusses Germany's placement of health high on the agenda of this year's G20 summit. It provides five recommendations with related policy actions, on topics that include Combating Antimicrobial Resistance, Fighting Neglected Tropical Diseases, and Improving Pandemic Preparedness and Response. (PDF)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Authors: Source Type: news

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Authors: Abstract How to assess global health at the close of 2018 and project achievable goals for the new year? WHO began on a somber and urgent note by identifying Ten Threats to Global Health in 2019. They are: air pollution and climate change; noncommunicable diseases; global influenza pandemic; fragile and vulnerable settings; antimicrobial resistance; Ebola and other high-threat pathogens; weak primary health care; vaccine hesitancy, dengue and HIV. Cuba is vulnerable to many of these threats, but perhaps more importantly, it's already taking them on, proposing more intersectoral actions to address social d...
Source: MEDICC Review - Category: International Medicine & Public Health Tags: MEDICC Rev Source Type: research
Conclusionsthis study highlights the importance of surveillance of XDR strains, even outside densely populated cosmopolitan regions, to reveal the epidemiology of pandemic lineages, stressing their threat to public health.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Source: U.S. House of Representatives, Committee on Oversight and Government Reform. Published: 6/26/2019. This one-hour, 22-minute Congressional hearing evaluates the readiness of the U.S. government and healthcare system, including hospitals and emergency professionals, to respond to naturally-occurring pandemics and biological attacks that could be perpetrated by state and non-state actors. It also investigates the growing threat of antimicrobial-resistance, as well as the implications of this challenge for U.S. national security. It discusses three key measures needed to curtail the spread of antibiotic resistance: in...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news
As resistance to antibiotics grows, the World Health Organization (WHO) has launched the latest stage of its campaign to fight this deadly health risk – likened by the agency to an “invisible pandemic”– with the launch of a new online tool for health professionals on Tuesday.
Source: UN News Centre - Health, Poverty, Food Security - Category: International Medicine & Public Health Source Type: news
Publication date: Available online 5 June 2019Source: Journal of Global Antimicrobial ResistanceAuthor(s): Mohammad Ahmad, Asad U. KhanAbstractThe pandemic of antibiotic resistance has become a serious threat to the therapeutic efficacy of the available antibiotics and their prescribed regimen. The problem is multifaceted as it encompasses medical, social, economic and anthropogenic spheres. The present review reports the global economic impact of antibiotic resistance among humans on the basis of published researches and reports of national and international organizations. The impacts are catastrophic because it includes ...
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Antimicrobial resistance (AMR) is an important factor for consideration in pandemic preparedness. Any reduction in treatability poses a potential risk to national and international security and economic stability when applied to pandemic-related pathogens (McArthur and Tsang, 2017). Increasing AMR among pathogens responsible for the development of community-acquired pneumonia (CAP) (e.g. Streptococcus pneumoniae and Haemophilus influenzae) (Adam, 2002) is especially concerning given their propensity to cause bacterial infections secondary to viral influenza.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
This study reports the occurrence of multidrug resistant V. cholerae O1 in Lake Victoria that are genetically closely related to recent pandemic strains in Tanzania, Kenya and Uganda. The strains identified are also closely related to older pandemic strains recovered in the Democratic Republic of Congo, Burundi and Tanzania up until 1993, suggesting a long-term persistence and wide spatial distribution of pandemic strains within the region with the lake serving as a reservoir. These environmental isolates likely emerged from previous cholera outbreaks and survived in the lake environment for decades through various relatio...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusions: We present the most detailed genomic analysis of MRSA isolated in Sri Lanka to date. The analysis identified a PVL-positive ST5-MRSA-IVc that is prevalent among MRSA causing clinical infections in Sri Lanka. Furthermore, this clone was also found among isolates from the United Kingdom and Australia. Introduction Worldwide, Staphylococcus aureus is the primary causative agent of community-acquired skin and soft tissue infections (SSTI) and is an important cause of hospital-associated invasive infections including bacteremia, pneumonia and endocarditis (Bell et al., 2002; David and Daum, 2010). Panton-Va...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Conclusions In conclusion, this investigation indicated that citral attenuated multiple virulence factors of V. parahaemolyticus, including QS, motility, biofilm formation, the adhesion to Caco-2 cells, and repressed the expression of genes related to flagella (polar and lateral), biofilm and T3SS1 effectors, virulence regulators (luxS, aphA and toxR), and AMP resistance. The results obtained in this work demonstrate the inhibitory effect of citral on virulence factors of V. parahaemolyticus. However, the data reported in this study only demonstrate the anti-virulence effect of citral in vitro. Further research is needed ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
This study identified prophages as mediators of bacterial virulence in a model of infectious endocarditis, probably through promotion of interaction with extracellular matrix components. Further studies are needed to identify mechanisms leading to promotion of intrinsic virulence. Introduction Challenges related to Staphylococcus aureus infections in the human and veterinary clinics mobilized important human and technical resources. S. aureus can colonize 20–30% of the general population asymptomatically but is also capable of causing a wide spectrum of diseases ranging from benign infections, to particularly...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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