Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal mice
Conclusions
Our results support a pathogenic role for enterocyte CaCCs in rotaviral diarrhoea and demonstrate the antidiarrhoeal action of CaCC inhibition by an alcohol-free, red wine extract and by a synthetic small molecule.
Source: Gut - Category: Gastroenterology Authors: Ko, E.-A., Jin, B.-J., Namkung, W., Ma, T., Thiagarajah, J. R., Verkman, A. S. Tags: Pancreas and biliary tract, Diarrhoea Colon Source Type: research
More News: Alcoholism | Calcium | Children | Chloride | Cholera | Cystic Fibrosis | Dialysis | Diarrhoea | Gastroenterology | Pancreas | Perinatology & Neonatology | Rotavirus