Hypopituitarism in children with cerebral palsy

We present a series of four children with cerebral palsy who were born before 29 weeks gestation who were referred to the regional endocrinology service, three for delayed puberty and one for short stature, in whom investigations identified MPHD. All patients had a height well below –2 standard deviation score (2nd centile) at presentation and three who had MRI scans had an ectopic posterior pituitary gland. We therefore recommend that the possibility of MPHD should be considered in all children with cerebral palsy and poor growth or delayed puberty. Early diagnosis and treatment is essential to maximise growth and prevent associated morbidity and mortality.
Source: Archives of Disease in Childhood - Category: Pediatrics Authors: Tags: Epidemiologic studies, Cerebral palsy, Reproductive medicine, Child health, Radiology, Sexual health, Clinical diagnostic tests, Radiology (diagnostics), Pituitary disorders Case report Source Type: research