Front-end genomics: using an alternative approach for the recovery of high-quality DNA from core needle biopsies

Conclusions Although more starting material in terms of the number of cells was present in both the FFPE and frozen section samples than the wash samples, equivalent to better results were obtained from the latter with regard to quality. This approach may be a means to better aliquot the diminutive amounts of tissue associated with core needle biopsies, allowing dissociated cells to be dedicated for molecular studies while keeping the tissue intact for morphological studies.
Source: Journal of Clinical Pathology - Category: Pathology Authors: Tags: JCP Education, Clinical diagnostic tests Original article Source Type: research