The incidence of IgG4-positive plasma cells staining TIN in patients with biopsy-proven tubulointerstitial nephritis
Conclusions
A number of cases of IgG4-positive plasma cell TIN were observed histologically that had been previously diagnosed as non-specific chronic TIN. IgG4-positive plasma cell TIN made up 1% of all renal biopsies performed over 10 years and 13% of all biopsies demonstrating TIN not related to glomerular disease. IgG4 staining should be considered routinely in biopsies demonstrating primary TIN.
Source: Journal of Clinical Pathology - Category: Pathology Authors: Mac, K., Wu, X. J., Mai, J., Howlin, K., Suranyi, M., Yong, J., Makris, A. Tags: Immunology (including allergy), Clinical diagnostic tests, Ethics Original article Source Type: research
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