Preventing Parkinson disease by vagotomy: Fact or fiction?

Aggregation of the neuronal protein α-synuclein into insoluble filamentous inclusions may be a determining factor in the development of Parkinson disease (PD). Converging evidence has demonstrated that α-synuclein inclusions have prion-like properties, including cell-to-cell transmission and the ability to induce native α-synuclein to misfold, thus setting the stage for domino-like spreading of cellular pathology.1

Source: Neurology - May 22, 2017 Category: Neurology Authors: Borghammer, P., Hamani, C. Tags: Parkinson's disease/Parkinsonism, Cohort studies EDITORIALS Source Type: research