Effects of L-DOPA/benserazide co-treatment on colonic excitatory cholinergic motility and enteric inflammation following dopaminergic nigrostriatal neurodegeneration.

CONCLUSION: Under dopaminergic nigrostriatal denervation, treatment with L-DOPA/BE ameliorated colonic motility through a normalization of myenteric cholinergic neurotransmission, along with an improvement of colonic inflammation. PMID: 28526609 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28526609?dopt=Abstract

Source: Neuropharmacology - May 16, 2017 Category: Drugs & Pharmacology Authors: Pellegrini C, Antonioli L, Colucci R, Tirotta E, Gentile D, Ippolito C, Segnani C, Levandis G, Cerri S, Blandini RF, Barocelli E, Ballabeni V, Bernardini N, Blandizzi C, Fornai M Tags: Neuropharmacology Source Type: research