Intimal sarcoma diagnosed by aspiration of in-stent thrombus during percutaneous coronary intervention

We examined the red thrombi histopathologically. Hematoxylin and eosin staining revealed high-grade spindle cell sarcoma with variable degrees of atypia and nuclear polymorphism (Panel E). There were no specific findings in the Whole-body Positron Emission Tomography and Computed Tomography scan. To confirm the definitive diagnosis, she underwent coronary artery bypass surgery (saphenous vein graft to RCA) 4 months after PCI. During the surgery, two small solid masses were detected on the surface of the distal RCA. Intraoperative biopsy confirmed intimal sarcoma. Cryothermy coagulation was performed during the surgery, and postoperative adjucvant chemotherapy was continued for one year. This case suggests that aspiration of recurrent in-stent thrombus helps to diagnose the pericardial malignant tumor.
Source: European Heart Journal - Category: Cardiology Source Type: research