High resolution manometry compared with theuniversity of california, los angeles scleroderma clinical trials consortium GIT 2.0 in systemic sclerosis

Systemic Sclerosis (SSc) is a multisystem connective tissue disorder of unknown etiology. The gastrointestinal tract (GIT) is affected in about 90% of patients [1,2] and gut involvement is the leading cause of morbidity and the third most common cause of mortality in these patients [3]. Any part of the GIT can be affected, leading to a wide range of symptoms from gastro-esophageal reflux disease (GERD) to fecal incontinence [4 –7]. The GIT involvement in SSc has a negative impact on health-related quality of life (HRQOL) [8,9].

Source: Seminars in Arthritis and Rheumatism - May 19, 2017 Category: Rheumatology Authors: Hanan Sayed M. Abozaid, Hala M.K. Imam, Marwa Mahmoud Abdelaziz, Dina el Hammady, Nihal A. Fathi, Daniel E. Furst Source Type: research