Early postoperative treatment of thyroidectomy scars using botulinum toxin: A split‐scar, double‐blind randomized controlled trial

Abstract Operational scars, especially those located on the exposed parts of the body can be distressful. Despite high demand for an early intervention to minimize surgical scars, there is yet no universal consensus on optimal treatment. A split‐scar, double‐blind randomized controlled trial was held to assess the safety and efficacy of early postoperative botulinum toxin type A (BTA) injection in surgical scars. A single session of treatment was performed where BTA was allocated to one half of the scar, and 0.9% saline to the control half. Scars were assessed using the modified Stony Brook Scar Evaluation Scale (SBSES) with standardized photographs. Fifteen patients completed the study and were analyzed. At 6 months follow‐up, a significant improvement in SBSES was noted in the BTA treated half of the scar (p <0.001) with minimal change on the saline treated side (P =0.785). The mean calculated difference in SBSES scores (final‐initial) between the BTA treated side and the saline treated side was also significant (p <0.001). Early postoperative BTA injection was safe and effective in modulating thyroidectomy scars and may be a promising option for scar prevention.
Source: Wound Repair and Regeneration - Category: Surgery Authors: Tags: Original Research‐Clinical Science Source Type: research