Isoquinoline alkaloids isolated from three Guatteria species

Publication date: August 2017 Source:Biochemical Systematics and Ecology, Volume 73 Author(s): Anderson R. dos Santos, Cassiano Pires, Francisco A. Marques, Adriana Q. Lobão, Beatriz Helena L.N.S. Maia The chemical investigation of the aerial parts of Guatteria ferruginea collected in the National Park of Serra dos Órgãos, Teresópolis, Brazil and of Guatteria latifolia and Guatteria sellowiana collected in the National Park of Itatiaia, Itatiaia, Brazil resulted in the isolation and identification of six isoquinoline alkaloids, two aporphine alkaloids 3-hydroxy-nornuciferine (1), nornuciferine (2) and four oxoaporphine alkaloids lysicamine (3), isomoschatoline (4), liriodenine (5) and O-methylmoschatoline (6). The isoquinoline alkaloids were found in the species G. ferruginea, G. latifolia and G. sellowiana for the first time and they support the taxonomic position within the genus Guatteria. Isoquinoline alkaloids (5–6) can be considered chemotaxonomic markers of the subfamily Annonoideae. Graphical abstract

Source: Biochemical Systematics and Ecology - May 19, 2017 Category: Biochemistry Source Type: research