06.05.14 -- Researchers Create Miniaturized, Artificial 3D Human Lung

06/05/14 Med Device Online Newsletter
Source: Medical Design Online News - Category: Medical Equipment Source Type: news

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Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Source Type: research
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Source Type: research
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Source Type: research
Conclusion Multiparametric pulmonary MRI is feasible in lung allografts within an EVLP system. Oxygen-enhanced imaging seems to be a promising marker for ischemic injury, enabling detection of affected lung segments prior to transplantation.
Source: Academic Radiology - Category: Radiology Source Type: research
We examined this interplay and response to mTOR inhibition using ERα+ adenocarcinomas from NRL-PRL females in combination with Col1a1tmJae/+ (mCol1a1) mice, which accumulate collagen-I around growing tumors. Orthotopic transplantation of tumor cells to mCol1a1 but not wildtype hosts resulted in striking desmoplasia.
Source: Cancer Letters - Category: Cancer & Oncology Authors: Tags: Original Articles Source Type: research
One challenging and controversial aspect of the perioperative management of patients undergoing lung transplantation is managing postoperative pain. Because the etiologies for transplantation, the patient populations, the surgical approaches, and the use of mechanical assistance either as extracorporeal membrane oxygenation (ECMO) or cardiopulmonary bypass (CPB) are so diverse, it is difficult to standardize a regimen for treating postsurgical pain in these patients.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Editorial Source Type: research
Conditions:   Advanced Lung Disease;   Lung Transplant;   Extracorporeal Membrane Oxygenation Interventions:   Device: MRP and NMES(neuromuscular electric stimulation);   Other: Standard of Care Sponsor:   University of Maryland Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Idiopathic Pulmonary Fibrosis;   Lung Transplant; Complications Interventions:   Drug: Nintedanib;   Drug: Placebo Oral Tablet Sponsors:   Temple University;   Boehringer Ingelheim Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Advanced Lung Disease;   Lung Transplant;   Extracorporeal Membrane Oxygenation Interventions:   Device: MRP and NMES(neuromuscular electric stimulation);   Other: Standard of Care Sponsor:   University of Maryland Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Idiopathic Pulmonary Fibrosis;   Lung Transplant; Complications Interventions:   Drug: Nintedanib;   Drug: Placebo Oral Tablet Sponsors:   Temple University;   Boehringer Ingelheim Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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